trials and regulatory affairs
A special showcase of top 10 Chinese innovative device companies and top 5 selected US/EU device companies interested in China

。【报名回执】访问此链接填写报名回执（https://www.wjx.top/jq/80710449.aspx）【咨询请联系】QQ 号：2814500767邮箱

会议简介

According to Business Insights, an estimated $25bn worth of biologics will lose patent protection by 2016, creating a significant market opportunity for biosimilars. However, the reality is that biosimilar development is a risk-fraught activity that demands significant resources in R&D, manufacturing expertise, regulatory know-how, clinical-trial capabilities, and a high level of financial investment.

Biosimilar development is riddled with complexities, ranging from regulatory, to manufacturing to marketing, and is one of the most expensive propositions in the pharmaceutical industry. It is estimated that it costs between US$100-200 million to bring a biosimilar product to market. With so much at stake, biosimilars represent not only substantial growth but equally risk..

IBC’s 2nd Annual Biosimilars Asia 2011 Summit is the ONLY conference in Asia catering to this region’s specific queries. With unprecedented insights from leading innovators and biosimilar companies, you will network and learn how to strategically position your company to maximize your ROI. Biosimilars Asia 2011 is attended by key stakeholders in the region and beyond, enabling you to make informed strategic decisions.

Register Now

PAYMENT TERMS

Payment must be received 10 business days prior to the event. To take advantage of discounts with an expiry cut-off date, registration and payment must be received by the cut off date.

Payments by Singapore Dollars (S$)

Payments by RMB (CNY)

• Payment by telegraphic transfer in CNY must be made to:
  A/C Name:
  A/C No.: 720-031103-001
  Beneficiary Bank:
  Bank Address: No. 1000 Lujiazui Rind Road,
  Pudong, Shanghai 200120, P.R. China
  Bank Swift Code: HSBCCNSH

CANCELLATIONS SUBSTITUTION
Should you be unable to attend, a substitute delegate is welcome at no extra charge. Cancellations must be received in writing at least 10 business days before the start of the event, to receive a refund less 10% processing fee per registration. The company regrets that no refund will be made available for cancellation notifications received less than 10 business days before the event.IMPORTANT NOTE:
Please quote the name of the delegate, event title and invoice number on the advice when remitting payment. Bank charges are to be deducted from participating organisations own accounts. Please fax your payment details (copy of remittance advice, cheque or draft to +65 6508 2407.

Attendance will only be permitted upon receipt of full payment. Participants wishing to register at the door are responsible to ensure all details are as published. IBC Asia will not be responsible for any event re-scheduled or cancelled.


DATA PROTECTION
The personal information entered during your registration/order, or provided by you, will be held on a database and may be shared with companies in the Informa Group in the UK and internationally. Sometimes your details may be obtained from or shared with external companies for marketing purposes. If you do not wish your details to be used for this purpose, please contact Winnie Seah (Database) on winnie.seah@ibcasia.com.sg Tel: +65 6508 2468 or Fax: +65 6508 2408.

）（即 S2TOP-BLEED 评分模型，见表1）。表 1 预测严重出血的S2TOP-BLEED 评分（来自多变量 Cox 回归模型）具体评分方法为，根据患者临床特征评估 S2TOP-BLEED 评分列表中每一栏分值，除了年龄相关的项目外，将其他所有项目分值想加得总分，再将总分代入图 1 所示风险分布图中，得到不同

明，使用远程医疗工具，如电话，互动视频和共享电子病历进行的多学科PTSD非现场干预，即创伤后应激障碍远程医疗服务（TOP）与常规护理（UC）相比，治疗效果显著提升...包括了2009年11月至2011年9月份在CBOCs接受治疗的265名主要生活在农村的退伍军人。所有患者均符合PTSD诊断标准，他们被随机分配接受TOP治疗（N

, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC

之一，抑郁的情绪和不科学的饮食也会导致。所以我们开处方让她进行调理，我们开出 ABC 处方进行管理，A 是深度系统管理，B 是中度失衡、病情复杂的管理，C

知道危重患者抢救的 ABC。AIRWAY，是永远的无争议的 A，是重中之重。对这个 A，临床医生一定要 A 级戒备，决不可有半点疏忽大意。别的环节出了问题，未必

技术的规范应用仍需加强。必须承认，我们本科基础教育是有缺陷的，当面对呼吸重症患者时，我们缺的不是高大上的呼吸机，而是很多ABC的东西！在原发病的处理上我们需要思路

整形与美容5:30pm—5:50pm崔禹植(韩国)韩国综合鼻部整形治疗设计5:50pm—6:00pm讨论ABC厅 ：6:30pm—8:00

继发性耐药的另一个重要原因。Burger等发现长期口服伊马替尼可通过上调细胞表达ABC转运蛋白ABCG2和ABCB1，使细胞药泵表达上调，从而促使细胞内伊马替尼

）马耳山：如果是考试做选择题乍一看像是CUSHING医者仁心abc：我曾在内分泌科见到同样的病例，诊断为库欣综合征，查CT及MRI见双侧肾上腺

as adjuvants in the treatment of tumor pain. 『quiller』美国人疼痛问题由美国《ABC新闻》和“

到了 825 份说明书，经过后台小助手日以继夜的审核，最终角逐出「3 月说明书上传榜」前三名：Top 1: 楠楠一沐 有效说明书 43 份Top 2: Eric_xzt 有效说明书 20 份Top 3: dxy_00wxf3se

这点是无疑的，肿瘤研究是并且也将一直是科研用户最关注的点，那么紧接着就让我们看看中国的科研用户更关注哪些疾病的研究？最关注的疾病类型 TOP10从以上排名来看... (分别为：糖尿病和 HIV)，从某一个角度上说明了这两种疾病所受的关注度与肿瘤疾病不相上下。接着从用户检索的关键词中统计出了中国科研用户最关注的基因 TOP

重磅炸弹。按照Bloomberg的预测，2013年上市的新药经过5年的市场推广和培育，销售额top10的新药都将迈过10亿美元的门槛，2018年这10个新药的销售额...药物Xtandi同样备受关注，但 5年之后（即2017年）top10的销售总额预计仅为大约150亿美元，可以说完败于2013年。进入2014年， FDA在1~6

, SCI”还不是一个很容易的事情。无论如何，这仅仅是时间的问题，早晚的事情。数年前（2008年初），大呆曾经写过一个系列的博文《Top Journals 是标准吗》，对SCI这个问题有过比较系统的阐述，现在看来，当时的一些观点并没有过时。特别是，在Top Journals 是标准吗-7和Top

龄为14-42岁，平均24岁。术前行髋关节螺旋CT扫描并进行三维重建，使用“Top View”技术及Azuma分级对股骨头覆盖程度进行评估...^o（-10^o-18^o），Top View的股骨头覆盖率平均为63．5％（50％-77％）。术后平均外侧CE角为30．1^o（13^o-47^o），臼顶倾斜角