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2012.02.27 铝诱导的神经退化性疾病的毒性来源于铁的积累和活性氧(ROS)的产生

Neurobiol Aging 2012 Jan;33 (1): 199.e1-199.e12. [IF:6.634]Aluminum... and reactive oxygen species (ROS) production.Wu Z , Du Y , Xue H , Wu Y , Zhou
溶瘤病毒联合 PD-1/L1 抗体,最佳拍档或是打破瓶颈的法宝!

2022.11.10 溶瘤病毒联合 PD-1/L1 抗体,最佳拍档或是打破瓶颈的法宝!

恢复健康。参考文献:[1] Li K, Zhao Y, Hu X, et al. Advances in the clinical development...和有效性进行了综合分析。OVs 临床分期截至 2021 年 10 月 1 日,已开展的 OVs 的临床研究共 408 项。表 1 列出了大约 31 种 OVs
神经科的那些病例:进行性四肢无力 1 例

2016.08.29 神经科的那些病例:进行性四肢无力 1

女,24 岁, 右利手, 进行性双下肢无力 4 年, 双上肢无力 1 年。患者于 4 年前无明显诱因下出现双下肢无力,表现为上楼梯困难,需手拉扶手。症状进行性加重,1 年前出现走平地费力,下蹲起立不能。同时出现双上肢无力,表现为平举不能,梳头费力,但能正常持筷、握笔写字。当时外院查 CK>20000U/L,行
全口服药方案用于移植后基因1型HCV复发患者安全有效

2014.11.20 全口服药方案用于移植后基因1型HCV复发患者安全有效

,这些方案也受贫血及感染等副作用的制约。此前,全口服药、无干扰素的直接抗病毒治疗方案Ⅲ期临床试验在基因1型HCV患者中取得了很高的病毒学应答率。但新一代无干扰素治疗方案尚未在基因1型HCV复发的肝移植患者中进行验证。因此,由印第安纳大学医学院Paul Y. Kwo 教授牵头,组织美国多个大学及医院参与了CORAL-Ⅰ研究,旨在
现场照片1

2014.11.17 现场照片1

现场照片1
手术现场1

2014.11.14 手术现场1

手术现场1
斑马鱼-1

2014.11.06 斑马鱼-1

斑马鱼-1
实验室1

2014.04.18 实验室1

实验室1
2017 肿瘤介入治疗进展回顾—放疗栓塞篇

2018.01.24 2017 肿瘤介入治疗进展回顾—放疗栓塞篇

项研究中,作者介绍了安全性分析,这些患者以 1:1 的比例被随机分配到对照组和联合治疗组,两组分别单独使用索拉非尼或 90Y 放射栓塞联合使用索拉非尼。索拉非尼...介入治疗具有:「靶向、微创、安全、高效」的特点 [1],在肿瘤的综合治疗中发挥着重要的作用。肿瘤介入治疗可分为血管介入治疗和非血管介入治疗。血管内介入治疗主要包括

2012.09.19 2nd Asia-Pacific Osteoporosis and Bone Meeting

会议简介 WelcomeThe Presidents of IOF and ANZBMS along with the Local Organising Committee are pleased to invite you to participate in the IOF Regionals - 2nd Asia-Pacific Osteoporosis and Bone Meeting being held in conjunction with the ANZBMS Annual Scientific Meeting and JSBMR in September 4-8, 2011.The Asia-Pacific region is the largest growth market in the world in the bone field. As revealed by the IOF Asian Audit in 2009, it is anticipated that by 2050 more than 50% of all osteoporotic fractures will occur in Asia.With an active Asia-Pacific Office and 28 member societies from the Region,? IOF Regionals provide the first and only? annual opportunity for a truly Regional Meeting to occur in the Asia-Pacific Region.? IOF Meetings focus on clinical treatment of osteoporosis as well as cutting edge science in the field. ANZBMS meetings are the peak Bone and Mineral professional events in the Australian and New Zealand region and JSBMR serves the entire Japanese community with annual scientific meetings in the area of bone and mineral research.The Meeting format includes plenary sessions, abstract presentations, poster presentations and viewing, Meet-the-Expert sessions, satellite symposia, award presentations, workshops and several social events.We hope to see you there!John A. Kanis,
President - International Osteoporosis FoundationRebecca Mason,
President - Australian and New Zealand Bone & Mineral Society
Program ? ?
Please see below for a draft program at a glance and preliminary seminar topics and associated titles. Please keep posted for more program details.138,173);">PROGRAM AT A GLANCE - Please click here for a downloadable program at a glance138,173);">SEMINAR TOPICS
  • Biomechanics and Bone Measurement
  • Mark Forwood , "Why bones fail: structure and mechanics"
  • Ego Seeman , "Measuring microarchitecture"
  • Clinical Management of Osteoporosis I
  • Hiroshi Hagino , "Incidence and prevention of second hip fracture in Japan"
  • John Kanis , "To BMD or not to BMD?
  • Markus Seibel , "Fracture liaison services"
  • Clinical Osteoporosis Management II
  • Jacqui Center , "Osteoporosis Management and Mortality"
  • Toshio Matsumoto , "New strategies for treatment of osteoporosis"
  • Philip Sambrook , "Osteoporosis:? what should we measure, what should we check, whom should we treat, and with what?"
  • Fracture Risk Algorithms: Soothsaying or Science?
  • Emma Duncan , "Genetics, bones and fracture"
  • John Kanis , Getting to Grips with FRAX: how it really works
  • Male Osteoporosis
  • Shigeaki Kato , "Estrogens, androgens and bone"
  • Eric Orwoll , "Osteoporosis in men"
  • Malignancy and Bone
  • Cory Xian , "Mechanisms and prevention for cancer chemotherapy-induced bone defects"
  • Toshio Yoneda , "Bone pain associated with cancer metastasis to bone"
  • Andrew Zannetino , "Myeloma and bone"
  • Non-Canonical Bone
  • Paul Baldock , "Bones and brains"
  • Caryl Nowson , "Bones and salt: the renin/angiotensin/aldosterone axis in bone"
  • Matthew Warman , "LRP5, serotonin and bone"
  • Osteoclasts
  • Natalie Sims , "Osteoblastic support of osteoclasts"
  • Nao Takahashi , "Quiescent osteoclast precursors"
  • Sanuo Takeshita , "Couplin"
  • Sakae Tanaka , "Regulation of activity and apoptosis of osteoclasts"
  • Osteoporosis in Oceania / Asia Pacific Region
  • Cyrus Cooper, "Secular trends in fracture incidence: Why are fractures increasing in Asia but falling in the West?"
  • Edith Lau , "Strategies for fracture prevention in Asia - where do we go from here?"
  • Ambrish Mithal , "Strategies to overcome epidemic of Vitamin D deficiency in Asia"
  • Paediatric Bone Disease
  • Christopher Cowell , "Measuring a growing skeleton, and the effect of ethnicity on bone and body composition"?
  • Keiichi Ozono , "Osteoporosis and Osteopetrosis in the young"
  • Tania Winzenberg , "Nutrition and bone in children"
  • Paget''s Disease
  • Tim Cundy , "The epidemiology of Paget''s disease"
  • Stuart Ralston , "The genetics of Paget''s disease"
  • Rheumatology and Bone
  • Steven Goldring , "Inflammation and bone resorption in Rheumatoid Arthritis"
  • Hiroshi Takayanagi , "Osteoimmunology"
  • Gethin Thomas , "Inflammation and bone formation in Ankylosing Spondylitis"
  • Skeletal Dysplasias
  • Seiji Fukumoto , "Hypophosphataemia and FGF23"
  • Matthew Warman , "Mouse models for Skeletal Dysplasias"
  • Andreas Zankl , "Skeletal dysplasias: a new approach"
  • The Effects of Ageing
  • Neil Binkley , "Sarcopaenia and ageing"
  • David Scott , "Sarcopaenia and Vitamin D"
  • Therapeutics in Osteoporosis: Controversies
  • Peter Ebeling , "The perils and pitfalls of antiresorptives"
  • Satoshi Mori , "Fracture healing- tissue changes with bisphosphonates"
  • Alvin Ng , "Atypical Subtrochanteric and Diaphyseal Femoral Fractures - What We Know and What We Don''t"
  • Speaker to be confirmed , "The positives of bisphosphonates"
  • Workshop on Bone Regeneration
  • Simon Cool , "Stem cells and fracture repair"
  • Yunfeng Lin , "Adipose Stem Cells and Craniofacial Regeneration"
  • Hala Zreiqat , "A basis for building bone:? novel nanocomposite scaffolds for new bone growth"

2023.05.06 Nature 子刊都在做的膜蛋白研究,1 小时教你稳抓热点

2022 年 6 月 2 日,清华大学团队在 Nature Cell Biology在线发表文章[1],报道了四次跨膜蛋白 Tetraspanin...有效;兼性离子型结合了离子型和非离子型去垢剂的优点,以 CHAPS 为代表,通常用于膜蛋白结晶。内容策划:邹礼平内容审核:周育红题图来源:图虫创意参考文献[1

2014.09.16 N1展馆

N1展馆

2015.12.09 2015新加坡第十六届东盟神经科学会 (ASEAN)

大会源流2015第16届东盟神经科学(ASEAN)和东盟联合11届神经学协会神经外科大会有史以来第一次的联合会议。东盟2015神经是由新加坡临床神经科学学会主办。东盟神经科学大会提供一个自由沟通平台为来自各国的神经病学家,杰出的神经外科医生,和其他医疗保健专业人员。2015新加坡第十六届东盟神经科学会 (ASEAN)将于7月30-31日在新加坡召开。主办单位东盟神经科学(ASEAN)组委会成员东盟神经科学(ASEAN)主席:Y ...
自然:癌症基础研究被指大多不可靠

2012.04.12 自然:癌症基础研究被指大多不可靠

前安进公司研究员发现,很多有关癌症的基础研究——很大一部分来自大学实验室——都是不可靠的。这一发现为研制新药的前景蒙上阴影。6X#n%w.Y!@'x8JC·格伦·贝格利曾担任安进公司全球癌症研究工作的负责人长达10年之久。他的科研小组对享有盛名的实验室发表在一流杂志上的53份“里程碑式”研究论文进行鉴定。贝格利希望能在以这些论文为基础的新药研发之前确保这些研究发现的可靠性。结果是,这5 ...
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