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2012.09.19 2011年世界高血压联盟区域大会暨第13届国际高血压及相关疾病学术研讨会

://www.whlrc2011.com/或联系大会秘书处:021-61333077;summitenquiry@elsevier.comThe 3.5... by hypertension to the communities and methods by which these may be prevented.2
二甲双胍可抑制分化型甲状腺癌生长

2013.06.08 二甲双胍可抑制分化型甲状腺癌生长

癌细胞生长,激活CAMP诱导蛋白激酶(AMPK)和下调p70S6K/pS6。二甲双胍加强H2O2诱导的AMPK激活,但减弱pERK和p70S6K。MF+患者的肿瘤...中,p70S6K/PS6可能是二甲双胍的分子靶位。该研究结果在线发表在2013年5月24日的《临床内分泌代谢杂志》(The journal of clinical
Andras Szasz

2017.11.08 Andras Szasz

Andras SzaszHungary(匈牙利)简介:András Szász 教授,首席科学家、教育学家。同时,他也是将深部热疗应用于肿瘤治疗的创始人。主要...:Prof. Dr. András Szász is the founder of the method oncothermia and also the company

2013.01.08 2003年JNC7-美国高血压指南

are the report’s key messages:In persons older than 50 years, systolic blood... that the responsible physician’s judgment remains paramount.

2011.09.01 脊柱损伤瘫痪有望恢复?

cord injuries walk again, according to a study published in this week's...;If you have a big freeway going somewhere, then that's the fastest route
舒尼替尼:可延长肾癌患者术后的无病生存期

2016.10.19 舒尼替尼:可延长肾癌患者术后的无病生存期

辉瑞公司近日公布了索坦 ®(舒尼替尼)辅助治疗的 S-TRAC Ⅲ 期临床试验(舒尼替尼辅助治疗肾癌的试验)结果。试验结果显示在肾细胞癌(RCC)根治性手术后...主席研讨会上公布,同时还会在《新英格兰医学杂志》网站在线发表。辅助治疗可降低手术等初始治疗后癌症复发的可能性。「S-TRAC 的结果让我们深受鼓舞,因为这是首次

2012.09.19 北京大学口腔医院四手操作培训班

北京大学口腔医院主办的中华会继续教育项目“四手操作培训班”定于”定于2012年2月19日~24日在北京举办。与会代表可获得继续医学教育I类学分10学分。课程安排:2月19日全天日全天报到,2月20日—24日授课。培训费

2012.09.19 【免注册费】上海分子流行病学与GWAS会议国际研讨会

        分子流行病学再揭示人类复杂疾病遗传因素及其与环境因素相互作用发挥重要作用,为人类疾病的风险评估、预防和个性化治疗提供依据。全基因组关联分析(GWAS)为全面系统研究复杂疾病的遗传因素掀开了新的一页,为我们了解人类复杂疾病的发病机制提供了更多的线索。科学家已经在肥胖、糖尿病、冠心病、阿尔茨海默、乳腺癌、前列腺癌、肺癌、胃癌等一系列复杂疾病中进行了全基因组关联研究并找到疾病相关的易感基因,我国科学家也在银屑病、精神病和冠心病等方面开展了GWAS研究并取得成效。国家科技部最新公布了“常见重大疾病全基因组关联分析和药物基因组学研究”的863重点项目,吹响了我国大规模开展GWAS研究的号角。为了让更多的相关研究人员,特别是广大研究生了解GWAS的研究原理和方法,学会设计GWAS的研究和分析实验结果,同时在癌症领域分享海内外研究专家们的成功经验,并期待在GWAS方面进行交流合作,复旦大学和美国Van Andel 研究所将于2009年7月12-14日在上海联合举办上海分子流行病学与GWAS国际 研讨会, 期待各位同道免费参加,请有意者及时将回执返回联系邮箱。免注册费(食宿餐饮费用自理)。名额有限,报名从速!时间: 2009年7月12-14日
报到地点: 复旦大学卿云楼宾馆 上海市邯郸路220号,200433
会议地点: 复旦大学逸夫楼报告厅
联 系 人: 赵雪莹 高歌 联系电话: 021-55664495
回执邮箱: GWAS2009@gmail.com
 BackgroundRecent success of genome-wide association studies (GWAS) in the U.S. and Europe has lead to the identification of a large number of genetic variants that are associated with disease risk and progression, including those for cancer and cardiovascular diseases. The discovery of these genetic markers not only improves our understanding of disease etiology, but also contributes significantly to risk prediction, early detection, and targeted treatment of diseases.Although GWAS have been used in Chinese populations to identify Chinese-specific risk-associated genetic variants for several common diseases such as breast cancer and psoriasis, many more GWAS are needed for various diseases. A better understanding of the importance of GWAS and a better knowledge of study design and data analysis of GWAS will further promote broad application of GWAS in China. This symposium which will cover genetic epidemiology and GWAS in China is organized to serve this purpose. We have invited a group of experts in this area from the U.S. and China to share their experience in GWAS, and we hope to foster an environment which will encourage an open discussion among all participants.
Objectives• To better understand the potential applications of GWAS
• To address practical issues in study design, implementation, and data analysis of GWAS
• To promote interaction and collaboration among researchers who are interested in GWAS
• To explore other important studies after GWAS: gene-environment interaction, risk prediction, and functional analyses
• To consider issues and implications related to genomic and personalize medicine
Organizing committeeThe organizing committee consists of four members:
Dr. Jianfeng Xu (Co-Chair)
Dr. Daru Lu (Co-Chair)
Dr. Li Jin (Co-Chair ,Advisor)
Dr. Qingyi Wei (Co-Chair, Advisor)
PresentationsSession I: Genetic epidemiology and GWAS of cancer
• Breast cancer in Chinese populations Xiao-ou Shu
• Genetic association studies of skin cancer Jiali Han
• Genetic variants in the MC1R gene and risk of cutaneous melanoma Qingyi Wei
• Genetic association studies of lung cancer in Chinese populations Daru Lu
• Molecular epidemiology of hepatitis, liver cirrhosis and hepatocarcinoma Gangqiao Zhou
• Molecular epidemiology of stomach cancer Weimin YeSession II: Genetic epidemiology and GWAS of other diseases
• Genetic association studies of hypertension in Chinese populations Jiang He
• GWAS of Autoimmune Diseases (Psoriasis, etc.) in Chinese populations Wei Huang
• Molecular epidemiology of diabetes in Chinese populations Weiping Jia
• Molecular genetics study of hypertension in Chinese populations Dingliang Zhu
• Molecular epidemiology of hepatitis, liver cirrhosis and hepatocarcinoma Gangqiao ZhouSession III: Post-GWAS studies
• Genetic structure of Chinese population Li Jin
• High-throughput genotyping for GWAS and fine mapping studies Siqun Lilly Zheng
• Molecular genetics study of neural tube defect Hongyan Wang
• Risk prediction using genetic variants in prostate cancer Jianfeng Xu
• Gene-environmental interaction in smoking related cancer Zuo-Feng Zhang
• Cancer Somatic Genomics Bin TehSession IV: Short presentations by participants and discussion
Registration时  间: 2009年7月12-14日
报到地点: 复旦大学卿云楼宾馆大厅 上海市邯郸路220号 (200433)
会议地点: 复旦大学逸夫楼报告厅
联 系 人: 赵雪莹,高歌 (Shanghai, China);Tamara Adams (U.S.)
联系电话: 21-55664495 (Shanghai, China);336-713-7532 (U.S.)
回执邮箱: GWAS2009@gmail.com (Shanghai, China);tsadams@wfubmc.edu (U.S.)
Invited speakers (alphabetic)• Jiali Han, Ph.D., is an Assistant Professor of Medicine at Harvard Medical School. His major research areas are:
• Genetic epidemiology of skin cancer and breast cancer
• Genome-wide association studies
• Gene-environment interaction• Jiang He, M.D. Ph.D., is a Professor and Chair of Epidemiology, Tulane University School of Public Health., U.S.A. His major research areas are:
• Genetic epidemiology of hypertension
• Gene-nutrition interaction of cardiovascular disease• Wei Huang, Ph.D., is a Professor and Executive Deputy Director of Chinese National Human Genome Center at Shanghai, China. Her major research areas are:
• Genetic susceptibility to autoimmune diseases, cardiovascular diseases and cancer.
• Genome-wide association studies
• Genetic variants and association study• Weiping Jia M.D., is a professor of endocrinology at Shanghai Institute of Diabetes, Shanghai No.6 People’s Hospital, Shanghai Jiaotong University, Her major research area is:
• Molecular endocrinology and diabetes• Li Jin, Ph.D, is a Professor of Genetics and vice President of Fudan University, China. His major research areas are:
• Genetic and molecular epidemiology of lung cancer and glioma
• Genetics of metabolism diseases
• Genetic markers for population genetics• Daru Lu, Ph.D, is a Professor of Genetics and Vice Dean of School of Life Sciences, Fudan University, China. His major research areas are:
• Genetic and molecular epidemiology of lung cancer and glioma
• Genetics of metabolic disease• Xiao-ou Shu, M.D, Ph,D, is a Professor of Medicine in the Department of Medicine at the Vanderbilt University School of Medicine, U.S.A. Her major research areas are:
• Genetic and lifestyle predictors of cancer and other chronic diseases
• Cohort study methodology
• Incorporating biomarkers in risk prediction• Bin Teh, M.D, is a Distinguished Scientific Investigator at Van Andel Institute, U.S.A. His major research areas are:
• Translational cancer research
• Gene expression profiling
• Cancer genome high-throughput sequencing• Hongyan Wang, Ph.D, is a professor of genetics at School of Life sciences, Fudan University, China. Her major research area is:
• Molecular genetics and epidemiology of birth defects (deformity of neural tube, congenital heart disease, etc.)• Qingyi Wei, M.D, Ph.D, is a Professor of Epidemiology at The University of Texas M. D. Anderson Cancer Center, U.S.A. His major research areas are:
• Molecular epidemiology of DNA repair, apoptosis, and skin cancer and head and neck cancer
• Genetic susceptibility to cancer
• DNA repair and apoptosis phenotype markers• Jianfeng Xu, M.D, Dr.PH, is a Professor of Epidemiology and Cancer Biology and Director of the Center for Cancer Genomics at Wake Forest University School of Medicine, U.S.A. His major research areas are:
• Genetic epidemiology of prostate cancer
• Genome-wide association and fine mapping analysis
• Risk prediction using genetic markers and other clinicopathologic variables• Zuo-Feng Zhang, M.D., Ph.D, is a Professor of Epidemiology at UCLA School of Public Health, U.S.A. His major research areas are:
• Molecular epidemiology of smoking-related cancers
• Confirmation studies of SNPs identified in genome-wide association studies in smoking-related cancers
• Gene-environmental interaction between genetic markers and environmental factorsS. Lilly Zheng, M.D, is a Professor of Medicine and Director of the Genotyping Laboratory at Wake Forest University School of Medicine. U.S.A. Her major research areas are:
• High-throughput genotyping and sequencing
• Genetic epidemiology of prostate cancer• Gangqiao Zhou, Ph.D, is a Professor of Medical Genetics and Genomics in National Academy of Military Medical Science. His major research area is:
• molecular and genetics of complex diseases• Dingliang Zhu, M.D, is a professor of cardiology at Shanghai Institute of Hypertension, Shanghai, China. His major research area is:
• Molecular and genetics of cardiovascular diseases• Weimin Ye, Ph.D, is a Professor of Medical Epidemiology at Karolinska Institutet, Sweden. His major research areas are: Etiology of upper gastrointestinal diseases
• Topic of presentation: Molecular epidemiology of stomach cancer
 

2012.02.29 刘强:《Nature》撰文如何获取项目资助,个人简单总结

全文见:http://www.nature.com... science.本子要原创,具有科学性,确实是值得资助。2. Grant officers are generally looking

2011.12.20 科学家发现能够减少肺癌治疗副作用的新方法

和遗传学研究所纳米和基因调控研究中心主任,研究副主任,生化学家William S. Dynan说:“放疗是一种重要的治疗方法,但问题是存在较大的...表面受体。”为使得打击更直接,科学家将叶酸受体作为进入点,通过使叶酸与其受体抗体的片段ScFv 18-2化学结合构建复合物。这种复合物
Br J Pharmacol:E-52862剂量与大脑sigma-1受体相互作用的E-52862水平以及镇痛活性之间存在着直接关系

2012.09.07 Br J Pharmacol:E-52862剂量与大脑sigma-1受体相互作用的E-52862水平以及镇痛活性之间存在着直接关系

Sigma-1受体(S1R)是一种重要的神经性疼痛治疗的新药研发靶点,在神经性疼痛治疗方面迫切需要新药诞生。ESTEVE公司研发的E-52862是一种强效、高选择性的NCE(新药),由于作用机制新颖(S1R 拮抗作用),现在正对其在疼痛治疗方面的应用进行评估。截至目前,临床前模
NIA/AA 2011年美国阿尔茨海默病最新诊断标准

2012.04.28 NIA/AA 2011年美国阿尔茨海默病最新诊断标准

摘要美国国家衰老研究所 (National Institute of Aging ,NIA )和阿尔茨海默病学会(Alzheimer's Association,AA)成立一个专家组对1984年版阿尔茨海默病(Alzheimer's diseaseAD)痴呆的诊断标准进行修订

2020.03.03 医院汇首页banner3

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骨质疏松及其药物治疗

2013.06.19 骨质疏松及其药物治疗

骨质疏松症的主要特征-19Woman`s Health Initiative(WHI)-52...治疗药物-47主要内容-2中国绝经后妇女骨折患病率-9

2012.12.20 细菌性阴道病复发与性生活和避孕显著相关

墨尔本性健康中心的Catriona S. Bradshaw博士等人展开一项研究,研究结果在线发表在2012年12月12日的《临床感染性疾病》(Clincal...,并完成一份调查问卷。在治疗后的1、2、3和6个月,参试者自行采集和制备阴道涂片,并完成问卷。该研究的主要终点为NS=7-10。采用多因素分析(Cox

2012.05.30 柳叶刀传染病:质量低劣的抗疟疾药物导致治疗效果不佳和药物耐受

去的十年,在控制及消除疟疾方面,质量低劣的抗疟疾药物很可能危及其快速进展及投资”。他是支持该研究的NIH's Fogarty...采用假包装,36%属于假冒伪劣。撒哈拉以南非洲地区的21个国家的类似的调查提供了2,634种疟疾药物样品的数据。在这些样品中,超过三分之一的药品成分与标准
三军大学感染教研室:发疹性感染病

2012.03.30 三军大学感染教研室:发疹性感染病

A组溶血链球菌在人体内蔓延与临床疾病-62Koplik’s spots-28并发症...-85风 疹-51概述-2概述-52概述-10

2012.01.09 硫化氢可减少葡萄糖诱导的肾细胞损伤

中由高糖诱导产生损伤的蛋白。该文预计会在2012年年初发表。B.S.Kasinath,医学博士,是圣安东尼奥市超声医学的肾病专家和主治医师...硫化钠物质时,它能降低使肾脏受损的基质蛋白的合成。”Kasinath博士和他的团队的报道与此发现一致,称患有第1型糖尿病和第2型糖尿病的小鼠肾脏中促进
帕米膦酸钠或能对抗多种流感病毒

2011.09.14 帕米膦酸钠或能对抗多种流感病毒

流感病毒,包括H5N1禽流感病毒。这一研究成果公布在《实验医学期刊》上。文章的通讯作者是香港大学J.S. Malik Peiris,Lau和 Tu,对于...。通过实验,研究人员首先培养了具有人类免疫系统的小鼠,然后注入了H1N1流感、H5N1与H9N2禽流感等病毒,再用帕米膦酸盐治疗。结果接受帕米膦酸盐治疗的

2013.08.04 四名中国科学家《科学》发文探讨中国科技体制改革

科学网四位知名博主——曹聪、李宁、李侠、刘立在8月1日出版的《科学》(Science)上撰写题为《改革中国科技体制》(Reforming China's S&T System)的文章,为中国科技体制存在的问题把脉并提出改革的思路。以下为文章全文中文版: 
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