发表在12月的微生物制剂和化疗杂志上的一项研究表明，一种针对O157：H7大肠杆菌的新型抗菌蛋白可以提供一种方式来预防或治疗严重的食源性细菌感染。大肠杆菌感染的动物模型结果表明：由AvidBiotics公司开发的口服的蛋白质，可以预防性给药或腹泻后服用，它可以预防或治疗O157：H7大肠杆菌引起的腹泻和肠炎

, Ma L, Asubonteng J, Hu ZH, Siddiqi T, Ahmed S, Ghobadi A, Miklos DB, Lin Y, Perales MA, Lunning MA, Herr MM, Hill BT, Ganguly S, Dong H, Nikiforow S, Hooper M

Best Pract Res Clin Endocrinol Metab. 2018;32(4):343-354.[2] Wen X, Wen D, Zhang H, Zhang H, Yang Y. Observational study pelvic ultrasound a useful tool

Background. Increased pneumococcal loads are associated with severe outcomes. We determined the prevalence of pneumococcal DNA in blood specimens from patients hospitalized with acute lower respiratory tract infection and identified factors associated with invasive pneumococcal pneumonia, bacterial loads, and death.Methods. A total of 8523 patients were enrolled as part of prospective hospital-based surveillance. Blood was collected for quantitative pneumococcal (lytA) detection, and nasopharyngeal specimens were collected for detection of influenza virus and other respiratory viruses by real-time polymerase chain reaction.Results. Of 6396 cases (75%) with lytA results, 422 (7%) were positive for pneumococcal DNA. The prevalences of human immunodeficiency virus (HIV) and influenza virus were 51% (2965/5855) and 8% (485/6358), respectively. On multivariable analysis, HIV infection (adjusted odds ratio [aOR], 2.4; 95% confidence interval [CI], 1.6-3.6), influenza virus coinfection (aOR, 1.4; 95% CI, 1.2-2.1), oxygen therapy during admission (aOR, 1.6; 95% CI, 1.1-2.3) and in-hospital death (aOR, 2.1; 95% CI, 1.1-4.0) were significantly associated with increased pneumococcal load. Among lytA-positive patients, after adjustment for length of hospitalization, duration of symptoms, and oxygen therapy during admission, pneumococcal loads ≥10,000 DNA copies/mL (aOR, 3.6; 95% CI, 1.8-7.2) were associated with increased risk of death.Conclusions. HIV and influenza virus infections were associated with elevated pneumococcal loads, which, in turn, were associated with increased risk of death.

更高（13.0% vs 2.4%），以上 p < 0.001。甚至在风险校正并剔除机械通气患者后，使用吗啡是一个独立的死亡预测因子 [OR 4.84（95..., Diercks DB, Lopatin M, Fonarow G, Emerman CL. Morphine and outcomes in acute

7 月 18 日，杭州玉皇山庄附近，一辆电动自行车在行驶途中突然起火。父亲被紧急送往浙江大学医学院附属第二医院, 全身多处火焰烧伤 95% 三度 75%。后来...哪些配合？大面积烧伤患者的治疗，困难重重像 95% 三度 75% 烧伤病人，无论放在国内外任何一个大的烧伤中心进行治疗，难度都是非常大的。一、早期出现了多脏器

小宝宝由于消化系统、神经系统发育不完善，很容易出现便秘的现象，但在 1 岁及以上的健康儿童中，95% 以上的便秘为功能性便秘。（功能性便秘是指持续性排便困难...情况，建议就医儿童便秘的发生率为 3%-30%，其中 95% 以上是功能性便秘。对于常规治疗无效的宝贝，或伴有腹痛、呕吐、腹胀、体重不增等情况，请及时寻求医生的

1 月 24 日中午，河南省首批援冀医疗队 95 名队员圆满完成各项救援任务，胜利凯旋。一方有难，八方支援，1 月 13 日援冀医疗队出征，郑州人民医院 6...，河南省卫健委抽调郑州大学第一附属医院等 7 家驻郑省直医院和郑州市紧急医疗救援中心、郑州市中心医院等 8 家郑州市直单位的 95 人，组成河南省援冀医疗队，同时派出

骨化三醇合成。为了在社区老年人评估血浆FGF23浓度与骨矿密度（BMD）和髋部骨折的关系。来自美国科罗拉多大学医学院Joachim H lx教授及其团队进行了...相关（FGF23每加倍：0.02[95%CI 0.001,0.04]g/cm2和0.03[95%CI 0.01,0.06]g/cm2）。在8.2±