Background. Little is known about the epidemiology of oral human papillomavirus (HPV) in Latin America.Methods. Women (N = 5838) aged 22-29 in the control and vaccine arms of an HPV-16/18 vaccine trial in Costa Rica had oral, cervical, and anal specimens collected. Samples were tested for alpha mucosal HPV types (SPF10/LiPA25 version 1); a subset of oral samples (n = 500) was tested for cutaneous HPV types in the genera alpha, beta, gamma, mu, and nu.Results. In the control arm (n = 2926), 1.9% of women had an oral alpha mucosal HPV detected, 1.3% had carcinogenic HPV, and 0.4% had HPV-16; similar patterns for non-16/18 HPV types were observed in the vaccine arm. Independent risk factors for any oral alpha mucosal HPV among women in the control arm included marital status (adjusted odds ratio [AOR], 3.2; 95% confidence interval [CI], 1.8-5.7 for single compared to married/living as married), number of sexual partners (AOR, 2.4; 95% CI, 1.0-6.1 for ≥4 partners compared to 0-1 partners), chronic sinusitis (AOR, 3.1; 95% CI, 1.5-6.7), and cervical HPV infection (AOR, 2.6; 95% CI, 1.4-4.6). Detection of beta HPV was common (18.6%) and not associated with sexual activity.Conclusions. Unlike cutaneous HPV types, alpha mucosal HPV types were uncommon in the oral region and were predominately associated with sexual behavior.Clinical Trials Registration.

(趋势检验P=0.01)，摄入维生素E补充剂几乎可以将风险降低一半(HR 0.52， 95% CI 0.30 ~ 0.90)。研究人员认为，如果结论得到证实... 0.66， 95% CI 0.46 ~0.94 以及HR 0.60， 95% CI 0.40 ~0.89；趋势检验P=0.01)。与那些不使用维生素E补充剂的人

研究流程设计不适当性窦性心动过速（inappropriate sinus tachycardia，IST）是一种临床综合征，表现为静息状态下或轻微运动时出现窦性心动过速，这种心动过速与正常生理需要不相符，患者常表现出明显的心悸症状，Holter检查提示平均心率在95次以上。关于不适当性窦速的

，以常规剂量的他汀类药物对比安慰剂，其混合数据表明，胰腺炎风险降低23%（相对风险0.77，95%CI0.62to0.97,P=0.03），该结果来自苏格兰...胰腺炎发病率低，尽管这种差别并没有达到统计显著性(RR0.82,95%CI0.59to1.12,P=0.21)。这项发现发表在美国医学会杂志8月22/29期

可使胰腺炎发病风险降低23%(OR=0.77， 95%CI=0.62-0.97， P=0.03)。此外，研究人员在8月22日第29期的《Journal...患者胰腺炎发病风险降低，但此差异没有统计学意义(RR= 0.82，95%CI=0.59-1.12，P=0.21)。Preiss及其同事通过对7项以安慰剂为对照的

制冷剂R 290噪声级别58 dB(A)电压 / 频率220 – 240 V ~ / 50 Hz输入电流4.0 A制冷系统 / 除霜强制通风 / 自动温度范围−2

R 600a噪声级别49 dB(A)电压 / 频率220 – 240 V ~ / 50 Hz输入电流2.0 A额定功率145 W制冷系统 / 除霜强制通风