搜索到 1000 条关于 f92텔Dbchance☑️사업자DB문의ㅣ 的文章
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2014.01.07 表观遗传学的改变可对AML患者预后产生影响
实验组,共纳入355例患者。研究人员在训练集检测了7种基因(CD34,RHOC,SCRN1,F2RL1, FAM92A1,MIR155HG和VWA8
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2012.11.05 冠状窦口及走行于心外膜冠状静脉的解剖学研究
心中静脉存在瓣膜导致血管部分甚至接近完全堵塞。93%的心脏存在左心房静脉侧支,41%的心脏左心房静脉侧支中至少有一支直径大于3F。对于CRT左室电极置入的血管,左室中侧壁可见数个侧支,其中心中静脉的存在率为20%,侧后静脉的存在率为92%,前室间静脉的存在率为86%。左膈神经通过左室中侧壁的概率为45%。通过
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2012.05.21 急性失代偿性心衰患者二期临床试验显示尿皮质醇2能显著提高心输出量
阻力和交感神经的过度刺激。平均动脉基础血压显著降低(p<0.001),从92 +/- 3 mmHg到输注尿皮质醇2(n=27)后到80+/-3 mmHg...Neurocrine Biosciences公司的首席医疗官Christopher F. O'Brien说:“临床二期的研究表明,尿皮质醇2能够有效
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2012.09.19 首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
北京·2012年5月16-18日
上海·2012年5月21-23日尊敬的老师,您好!生理药代动力学模型(PBPK)在药物研发与监管中得到广泛应用意味着新时代的来临!它改变了动物试验和人体实验传统研究模式流程,指导制药企业项目决策及效率提高;FDA和EMA的使用及推荐,促使国外制药企业及学术单位相关研究者都在学习及掌握PBPK的应用。为促进我国在该领域的发展,力争与全球同步,凡默谷特邀美国Simulations Plus顶尖专家来华授课,让您了解及掌握PBPK知识、获悉国外最新应用、亲授多年使用经验,授课过程将以理论与实践相结合的形式进行。GastroPlus是由美国Simulations Plus公司研发的基于机制性生理模型的药代动力学、药效动力学(PBPK/PD)模拟软件,目前在FDA和几乎所有的全球顶尖制药公司中得到广泛应用,被誉为同类软件中的“黄金标准”。为确保培训效果,限额50人/班,第一轮通知发出后,已得到广大中国用户的积极响应和踊跃报名。报名从速!为何本次GastroPlus Workshop值得您参加?1)药物研发及监管中争相应用PBPK模型的时代已经来临!2)PBPK辅助药物研究可方便指导项目决策、节约成本、缩短时间;3)FDA已广泛采用PBPK模拟来制定法规和对新药及仿制药进行审批;4)FDA及各大制药企业对全球最权威的PBPK模拟软件GastroPlus倍加青睐;5)零距离接触Simulations Plus首席科学家,并参与学习的最新应用案例;6)您可免费获得一个月的GastroPlus软件试用。本次GastroPlus Workshop将让您受益良多:1)制药企业或CRO:有利于您理解您的客户或其他Sites实验方案设计思路、下一阶段决策及实验开展、合理设计实验方案;2)学术研究:启示您开辟新的药代、药剂等研究方向,剖析药物作用机制等;3)临床药理研究:合理设计临床试验方案,不同人群PK/PD研究等;4)法规部门:协助制定新药及仿制药政策和标准。报名方法:请您填写报名回执,并通过Email的方式反馈给我们。Email: training@pharmogo.com报名截止:2012年4月20日(北京培训班)/2012年4月30日(上海培训班)联系人:周伟,电话:021-61638583-8001报名确认:1)报名确认以凡默谷收到款项或报名者提供汇款凭证为准,凡默谷可先提供发票以供报销;2)会务组在接到报名后,将email或电话通知学员培训班相关事项。温馨提醒:学员必须自带已安装好Gastroplus程序的电脑参加培训,现场不提供电脑。
GastroPlus Workshop Course Instructors List
培训班详情:请下载附件参加北京培训班请点击下载:GastroPlus北京培训班第二轮通知/BeiJing GastroPlus-Intro-Workshop 2nd Notice参加北京培训班请点击下载:GastroPlus上海培训班第二轮通知/ShangHai GastroPlus-Intro-Workshop 2nd Notice
Michael B. Bolger
Chief Scientist
Simulations Plus Inc.
Dr. Bolger is Chief Scientist at Simulations Plus, he oversees a team of scientist / programmers at Simulations Plus, Inc. (Lancaster, CA) in the development of software programs (ADMET Predictor/Modeler, MedChem Studio/Designer, GastroPlus, DDDPlus, and MembranePlus) for estimation of biopharmaceutical properties, simulations of absorption and bioavailability, automated generation QSP/AR model building, in vitro dissolution, and cell culture permeability simulation.
As a faculty member at USC School of Pharmacy, his research was supported by several NIH basic science research grants and he published over 50 peer-reviewed publications. From 1989-1991 he served as a FDA National Science Advisor. He has served as a reviewer for numerous scientific publications. He is currently Adjunct Associate Professor of Pharmaceutical Sciences at USC.

Haiying Zhou, Ph.D.
Senior Scientist II
Simulations Plus Inc.
Dr. Zhou is Senior Scientist II at Simulations Plus, she focused on the development of modeling and simulation software for quantitative understanding of the pharmacokinetics and pharmacodynamics of drug candidates (GastroPlus), in vitro dissolution of active pharmaceutical ingredients and formulation excipients under various experimental conditions (DDDPlus). She received her M.S. degree in automation from East China University of Science and Technology (ECUST) in 2002 and her Ph.D in Biomedical Engineering from Case Western Reserve University (CWRU) in 2009. Her research interests in CWRU include multi-scale mathematical modeling of gas transport and cellular metabolism with emphasis on the metabolic regulation during different conditions, e.g. hypoxia and exercise.

John DiBella
Vice President of Marketing Simulations Plus Inc.
John DiBella is the Director – Marketing & Sales at Simulations Plus, He joined Simulations Plus in 2003 and has spent time working on the development of GastroPlus? and DDDPlus? software and consulting projects. Now, he leads the marketing & sales activities for the company while continuing to travel the world hosting training seminars.John obtained B.S. and M.S. degrees (with honors) in Biomedical Engineering from Case Western Reserve University in 2003. His graduate research was focused on computational modeling of physiological systems.
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2012.09.19 首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
北京·2012年5月16-18日
上海·2012年5月21-23日尊敬的老师,您好!生理药代动力学模型(PBPK)在药物研发与监管中得到广泛应用意味着新时代的来临!它改变了动物试验和人体实验传统研究模式流程,指导制药企业项目决策及效率提高;FDA和EMA的使用及推荐,促使国外制药企业及学术单位相关研究者都在学习及掌握PBPK的应用。为促进我国在该领域的发展,力争与全球同步,凡默谷特邀美国Simulations Plus顶尖专家来华授课,让您了解及掌握PBPK知识、获悉国外最新应用、亲授多年使用经验,授课过程将以理论与实践相结合的形式进行。GastroPlus是由美国Simulations Plus公司研发的基于机制性生理模型的药代动力学、药效动力学(PBPK/PD)模拟软件,目前在FDA和几乎所有的全球顶尖制药公司中得到广泛应用,被誉为同类软件中的“黄金标准”。为确保培训效果,限额50人/班,第一轮通知发出后,已得到广大中国用户的积极响应和踊跃报名。报名从速!为何本次GastroPlus Workshop值得您参加?1)药物研发及监管中争相应用PBPK模型的时代已经来临!2)PBPK辅助药物研究可方便指导项目决策、节约成本、缩短时间;3)FDA已广泛采用PBPK模拟来制定法规和对新药及仿制药进行审批;4)FDA及各大制药企业对全球最权威的PBPK模拟软件GastroPlus倍加青睐;5)零距离接触Simulations Plus首席科学家,并参与学习的最新应用案例;6)您可免费获得一个月的GastroPlus软件试用。本次GastroPlus Workshop将让您受益良多:1)制药企业或CRO:有利于您理解您的客户或其他Sites实验方案设计思路、下一阶段决策及实验开展、合理设计实验方案;2)学术研究:启示您开辟新的药代、药剂等研究方向,剖析药物作用机制等;3)临床药理研究:合理设计临床试验方案,不同人群PK/PD研究等;4)法规部门:协助制定新药及仿制药政策和标准。报名方法:请您填写报名回执,并通过Email的方式反馈给我们。Email: training@pharmogo.com报名截止:2012年4月20日(北京培训班)/2012年4月30日(上海培训班)联系人:周伟,电话:021-61638583-8001报名确认:1)报名确认以凡默谷收到款项或报名者提供汇款凭证为准,凡默谷可先提供发票以供报销;2)会务组在接到报名后,将email或电话通知学员培训班相关事项。温馨提醒:学员必须自带已安装好Gastroplus程序的电脑参加培训,现场不提供电脑。
GastroPlus Workshop Course Instructors List
培训班详情:请下载附件参加北京培训班请点击下载:GastroPlus北京培训班第二轮通知/BeiJing GastroPlus-Intro-Workshop 2nd Notice参加北京培训班请点击下载:GastroPlus上海培训班第二轮通知/ShangHai GastroPlus-Intro-Workshop 2nd Notice
Michael B. Bolger
Chief Scientist
Simulations Plus Inc.
Dr. Bolger is Chief Scientist at Simulations Plus, he oversees a team of scientist / programmers at Simulations Plus, Inc. (Lancaster, CA) in the development of software programs (ADMET Predictor/Modeler, MedChem Studio/Designer, GastroPlus, DDDPlus, and MembranePlus) for estimation of biopharmaceutical properties, simulations of absorption and bioavailability, automated generation QSP/AR model building, in vitro dissolution, and cell culture permeability simulation.
As a faculty member at USC School of Pharmacy, his research was supported by several NIH basic science research grants and he published over 50 peer-reviewed publications. From 1989-1991 he served as a FDA National Science Advisor. He has served as a reviewer for numerous scientific publications. He is currently Adjunct Associate Professor of Pharmaceutical Sciences at USC.

Haiying Zhou, Ph.D.
Senior Scientist II
Simulations Plus Inc.
Dr. Zhou is Senior Scientist II at Simulations Plus, she focused on the development of modeling and simulation software for quantitative understanding of the pharmacokinetics and pharmacodynamics of drug candidates (GastroPlus), in vitro dissolution of active pharmaceutical ingredients and formulation excipients under various experimental conditions (DDDPlus). She received her M.S. degree in automation from East China University of Science and Technology (ECUST) in 2002 and her Ph.D in Biomedical Engineering from Case Western Reserve University (CWRU) in 2009. Her research interests in CWRU include multi-scale mathematical modeling of gas transport and cellular metabolism with emphasis on the metabolic regulation during different conditions, e.g. hypoxia and exercise.

John DiBella
Vice President of Marketing Simulations Plus Inc.
John DiBella is the Director – Marketing & Sales at Simulations Plus, He joined Simulations Plus in 2003 and has spent time working on the development of GastroPlus? and DDDPlus? software and consulting projects. Now, he leads the marketing & sales activities for the company while continuing to travel the world hosting training seminars.John obtained B.S. and M.S. degrees (with honors) in Biomedical Engineering from Case Western Reserve University in 2003. His graduate research was focused on computational modeling of physiological systems.
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2012.12.28 冰冻与新鲜同种异体骨软骨移植治疗山羊关节软骨缺损模型的实验研究
标本移植组的细胞含量和基质成分较之非手术对照组或新鲜标本移植组分别低约96%(95%的可信区间,94% - 99%)和55%(95%的可信区间,22%- 92...对照组、冰冻保存组以及新鲜标本组在股骨内侧髁(A, B, C, G, H, I)和股骨滑车外侧面(D, E, F, J, K, L)采集的骨软骨标本,采用
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2012.06.08 郑煜煌教授:关爱生命,抗击艾滋
:我最近看到一篇文章Human APOBEC3F Is Another Host Factor That Blocks Human Immunodeficiency Virus Type 1 Replication文章说APOBEC3G, APOBEC3F introduces G to A
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2016.08.27 白衣天使风采
头颈外科三个病区共有护理人员 46 人,主任护师 1 人,硕士 3 人,专科护士 2 人,省优秀护士 1 人,院优秀护理人才 1 人,院青年护理人才 2 人,中级职称人员 16 人,本科率达 92%。
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2012.09.19 中英再生医学高峰论坛
主席:Prof. Z. F. Cui (崔占峰 教授 )与会专家:英 方 专 家Experts of UK Z. F. CUI... and challenges Z. F. CUI10:35-10:45 Discussion10:45-10:55 Break
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2012.02.17 细胞名称大汇总
Y1 (F12)肾上腺皮质细胞3T3-L1小鼠...细胞Hs 578Bst乳腺细胞NK-92
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2012.09.19 第十届全国眼科峰会暨全国重点学科建设与眼科管理及新技术进展方向研讨班
地址:http://blog.sina.com.cn/s/blog_51f8026b0100i2eo.html填完后请寄至:江苏省无锡市第二人
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2010.06.27 2010年第三届南方急危重症论坛议程
相约羊城,热切期盼,携手并进,共同参与!附件:F:\科室资料\2010年第三届南方急危重症论坛议程.ppt
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2011.11.20 Spine RCT:Grafton脱钙骨基质结合局部骨在单节段腰椎融合术中疗效肯定
部骨(n=30)或自体髂嵴骨(n=16)。DBM组平均年龄64岁(21F, 9M),ICBC组平均年龄65岁(9F, 5M)。由1名独立的放射科医师于术后6月、1...,GraftonMatrix组为86% ,ICBG组为92% (p=1.0 NS)。终末随访时,Grafton组的ODI评分和躯体功能评分略优于ICBG组,然而
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2011.12.28 患者,男,48岁,反复发热3月余,听力下降10余天,言语不清8天
73.1/97.4U/L TB/DB 14.7/7.0umol/lLDH:939.7u/l凝血功能: PT 14.5s血培养...: (08-03-09)阴性肝功能: (08-03-09)A/G 18.7/24.5g/L TB/DB 42.9/22.9umol/l ALT/AST
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2012.09.19 射频热凝靶点治疗颈肩腰腿痛新技术培训班
国家中医药管理局科技成果重点推广项目(国 中 推 第[2009] 50号)北京鑫泰鸿强医院管理有限公司新技术新成果推广中心射频热凝靶点治疗颈肩腰腿痛新技术培训班第 92 期尊敬的院长/主任:射频热凝靶点术治疗颈、腰椎间盘突出症是洪强医疗集团董事长刘洪强院长2004年在几万
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2011.09.13 研究人员发现极具潜力的眼肿瘤新疗法
Conkrite、Maggie Sundby和David MacPherson以及其他研究机构的研究重点是名为miR-17~92的miRNA簇。新近研究显示,这一簇miRNA的异常表达可防止癌变前细胞死亡,并令它们增殖成肿瘤。以前的工作已证实,miR-17~92能通过降低肿瘤抑制蛋白PTEN的水平而促进淋巴瘤和白血病
