International Meeting is Europe’s landmark meeting on Gynaecological Oncology and offers professionals an excellent opportunity to discover the latest

用于晚期难治性实体肿瘤患者的安全性、药动学及其抗肿瘤活性，来加州大学洛杉矶分校医学系的Lee S. Rosen和杜克大学医学中心的Herbert I....。在正在进行中的临床Ib期与临床II期研究中，未在TRC105(来源：中国仓鼠卵巢细胞)治疗的患者中检测到TRC105抗体。在45例可评价患者中，有21例出现病情

糖尿病引起酮症酸中毒并发上尿路感染、气肿性肾盂肾炎，继而全身浮肿陷入昏迷，69 岁的熊婆婆在「鬼门关」走了一遭。通过对症治疗，熊婆婆病情好转已于近日出院。暖心回顾家住县城的熊婆婆患有糖尿病 15 年，并且血糖一直控制不佳。近日，熊婆婆因腰腹疼痛，前往当地医院内分泌科就诊，治疗十余天后，症状不仅没有改善，反而

合江县人民医院位于四川省泸州市合江县合江镇酱园坪69号，是一所国家三级乙等综合医院。合江县人民医院创建于1940年8月，经过历代员工的不懈努力，现已发展成为集医疗、教学、科研、预防保健、康复及急救功能为一体的国家三级乙等综合医院。是国家爱婴医院、泸州市急救中心二级急救站、西南医科大学附属医院医联体医院，四川中医药

商业情报供应商 GBI Research 称，非小细胞肺癌（NSCLC）的全球治疗市场规模将由 2014 年的 69 亿美元增长到 2021 年的 109 亿美元，这代表 8.5% 的复合年增长率（CAGR）。该公司最新的报告《到 2021 年主要发达市的非小细胞肺癌治疗-免疫治疗药物的出现驱动市场增长并建立起一个

Acute leukaemia of ambiguous lineage-69Acute monocytic leukaemia-67Acute myeloid leukaemia-28 

】暂无【会议简介】The World's Premier Nephrology MeetingJoin ASN... 2014 in Philadelphia, Pennsylvania. The world’s premier nephrology meeting

或IMEs的新方法，华盛顿西雅图儿童医院和研究所Ringold S博士等开展了加强药物安全监测项目（EDSSP）的研究，对2008-2012年这4年里EDSSP的结果...39%和37%。大多数SAEs和IMEs发生在进行生物制剂治疗的患儿中：76%发生SAEs的患儿曾进行生物制剂治疗，69%发生MEs的患儿曾进行生物制剂治疗

一、病例介绍患者曾某女性，69 岁，发现乙肝表面抗原阳性 20 余年，乏力纳差，否认遗传及家族感染病。皮肤巩膜黄染，心听诊无异常，肝脾无触及，2015 年 6...二、诊疗思路分析 患者女性，69 岁，曾经接受过阿德福韦（ADV）, 富马酸替诺福韦酯（TDF）治疗，这类高龄的慢乙肝患者同时长期服用 NUC 为肾损害高危人群

majestic monuments, finest museums, shopper's paradise, courtly grace..., Ashok Vihar – Phase IIDelhi 110 052, INDIAPHONE

Venue: Expo Center Norte ExhibitionCenter - São Paulo– BRAZIL展会开放时间：中午 11：00-晚上...： São Paulo Trade Fairs 与 德国杜塞尔多夫展览集团公司联合主办 中国组织： 世展博览（集团）有限公司（IEX 

澳大利亚网站TGA提醒医务人员，坎地沙坦和其他血管紧张素II受体拮抗剂以及ACE抑制剂禁用于妊娠期。妊娠期暴露于上述药物可能导致胎儿毒性。已发生妊娠...和卡托普利后发生胎儿畸形的报告。血管紧张素II受体拮抗剂和ACE抑制剂被归为澳大利亚妊娠期用药的D类。此类药物禁用于妊娠期。作用于肾素-血管紧张

痛风性膝关节炎可导致Baker’s囊肿的形成，正确认识痛风和Baker’s囊肿的超声特征对于明确诊断和治疗意义重大。

        分子流行病学再揭示人类复杂疾病遗传因素及其与环境因素相互作用发挥重要作用,为人类疾病的风险评估、预防和个性化治疗提供依据。全基因组关联分析（GWAS）为全面系统研究复杂疾病的遗传因素掀开了新的一页，为我们了解人类复杂疾病的发病机制提供了更多的线索。科学家已经在肥胖、糖尿病、冠心病、阿尔茨海默、乳腺癌、前列腺癌、肺癌、胃癌等一系列复杂疾病中进行了全基因组关联研究并找到疾病相关的易感基因，我国科学家也在银屑病、精神病和冠心病等方面开展了GWAS研究并取得成效。国家科技部最新公布了“常见重大疾病全基因组关联分析和药物基因组学研究”的863重点项目，吹响了我国大规模开展GWAS研究的号角。为了让更多的相关研究人员，特别是广大研究生了解GWAS的研究原理和方法，学会设计GWAS的研究和分析实验结果，同时在癌症领域分享海内外研究专家们的成功经验，并期待在GWAS方面进行交流合作,复旦大学和美国Van Andel 研究所将于2009年7月12-14日在上海联合举办上海分子流行病学与GWAS国际 研讨会, 期待各位同道免费参加，请有意者及时将回执返回联系邮箱。免注册费（食宿餐饮费用自理）。名额有限，报名从速！时间： 2009年7月12－14日
报到地点： 复旦大学卿云楼宾馆 上海市邯郸路220号，200433
会议地点： 复旦大学逸夫楼报告厅
联 系 人： 赵雪莹 高歌 联系电话： 021-55664495
回执邮箱： GWAS2009@gmail.com
 BackgroundRecent success of genome-wide association studies (GWAS) in the U.S. and Europe has lead to the identification of a large number of genetic variants that are associated with disease risk and progression, including those for cancer and cardiovascular diseases. The discovery of these genetic markers not only improves our understanding of disease etiology, but also contributes significantly to risk prediction, early detection, and targeted treatment of diseases.Although GWAS have been used in Chinese populations to identify Chinese-specific risk-associated genetic variants for several common diseases such as breast cancer and psoriasis, many more GWAS are needed for various diseases. A better understanding of the importance of GWAS and a better knowledge of study design and data analysis of GWAS will further promote broad application of GWAS in China. This symposium which will cover genetic epidemiology and GWAS in China is organized to serve this purpose. We have invited a group of experts in this area from the U.S. and China to share their experience in GWAS, and we hope to foster an environment which will encourage an open discussion among all participants.
Objectives• To better understand the potential applications of GWAS
• To address practical issues in study design, implementation, and data analysis of GWAS
• To promote interaction and collaboration among researchers who are interested in GWAS
• To explore other important studies after GWAS: gene-environment interaction, risk prediction, and functional analyses
• To consider issues and implications related to genomic and personalize medicine
Organizing committeeThe organizing committee consists of four members:
Dr. Jianfeng Xu (Co-Chair)
Dr. Daru Lu (Co-Chair)
Dr. Li Jin (Co-Chair ,Advisor)
Dr. Qingyi Wei (Co-Chair, Advisor)
PresentationsSession I: Genetic epidemiology and GWAS of cancer
• Breast cancer in Chinese populations Xiao-ou Shu
• Genetic association studies of skin cancer Jiali Han
• Genetic variants in the MC1R gene and risk of cutaneous melanoma Qingyi Wei
• Genetic association studies of lung cancer in Chinese populations Daru Lu
• Molecular epidemiology of hepatitis, liver cirrhosis and hepatocarcinoma Gangqiao Zhou
• Molecular epidemiology of stomach cancer Weimin YeSession II: Genetic epidemiology and GWAS of other diseases
• Genetic association studies of hypertension in Chinese populations Jiang He
• GWAS of Autoimmune Diseases (Psoriasis, etc.) in Chinese populations Wei Huang
• Molecular epidemiology of diabetes in Chinese populations Weiping Jia
• Molecular genetics study of hypertension in Chinese populations Dingliang Zhu
• Molecular epidemiology of hepatitis, liver cirrhosis and hepatocarcinoma Gangqiao ZhouSession III: Post-GWAS studies
• Genetic structure of Chinese population Li Jin
• High-throughput genotyping for GWAS and fine mapping studies Siqun Lilly Zheng
• Molecular genetics study of neural tube defect Hongyan Wang
• Risk prediction using genetic variants in prostate cancer Jianfeng Xu
• Gene-environmental interaction in smoking related cancer Zuo-Feng Zhang
• Cancer Somatic Genomics Bin TehSession IV: Short presentations by participants and discussion
Registration时　　间： 2009年7月12－14日
报到地点： 复旦大学卿云楼宾馆大厅 上海市邯郸路220号 (200433)
会议地点： 复旦大学逸夫楼报告厅
联 系 人： 赵雪莹，高歌 (Shanghai, China)；Tamara Adams (U.S.)
联系电话： 21-55664495 (Shanghai, China)；336-713-7532 (U.S.)
回执邮箱： GWAS2009@gmail.com (Shanghai, China)；tsadams@wfubmc.edu (U.S.)
Invited speakers (alphabetic)• Jiali Han, Ph.D., is an Assistant Professor of Medicine at Harvard Medical School. His major research areas are:
• Genetic epidemiology of skin cancer and breast cancer
• Genome-wide association studies
• Gene-environment interaction• Jiang He, M.D. Ph.D., is a Professor and Chair of Epidemiology, Tulane University School of Public Health., U.S.A. His major research areas are:
• Genetic epidemiology of hypertension
• Gene-nutrition interaction of cardiovascular disease• Wei Huang, Ph.D., is a Professor and Executive Deputy Director of Chinese National Human Genome Center at Shanghai, China. Her major research areas are:
• Genetic susceptibility to autoimmune diseases, cardiovascular diseases and cancer.
• Genome-wide association studies
• Genetic variants and association study• Weiping Jia M.D., is a professor of endocrinology at Shanghai Institute of Diabetes, Shanghai No.6 People’s Hospital, Shanghai Jiaotong University, Her major research area is:
• Molecular endocrinology and diabetes• Li Jin, Ph.D, is a Professor of Genetics and vice President of Fudan University, China. His major research areas are:
• Genetic and molecular epidemiology of lung cancer and glioma
• Genetics of metabolism diseases
• Genetic markers for population genetics• Daru Lu, Ph.D, is a Professor of Genetics and Vice Dean of School of Life Sciences, Fudan University, China. His major research areas are:
• Genetic and molecular epidemiology of lung cancer and glioma
• Genetics of metabolic disease• Xiao-ou Shu, M.D, Ph,D, is a Professor of Medicine in the Department of Medicine at the Vanderbilt University School of Medicine, U.S.A. Her major research areas are:
• Genetic and lifestyle predictors of cancer and other chronic diseases
• Cohort study methodology
• Incorporating biomarkers in risk prediction• Bin Teh, M.D, is a Distinguished Scientific Investigator at Van Andel Institute, U.S.A. His major research areas are:
• Translational cancer research
• Gene expression profiling
• Cancer genome high-throughput sequencing• Hongyan Wang, Ph.D, is a professor of genetics at School of Life sciences, Fudan University, China. Her major research area is:
• Molecular genetics and epidemiology of birth defects (deformity of neural tube, congenital heart disease, etc.)• Qingyi Wei, M.D, Ph.D, is a Professor of Epidemiology at The University of Texas M. D. Anderson Cancer Center, U.S.A. His major research areas are:
• Molecular epidemiology of DNA repair, apoptosis, and skin cancer and head and neck cancer
• Genetic susceptibility to cancer
• DNA repair and apoptosis phenotype markers• Jianfeng Xu, M.D, Dr.PH, is a Professor of Epidemiology and Cancer Biology and Director of the Center for Cancer Genomics at Wake Forest University School of Medicine, U.S.A. His major research areas are:
• Genetic epidemiology of prostate cancer
• Genome-wide association and fine mapping analysis
• Risk prediction using genetic markers and other clinicopathologic variables• Zuo-Feng Zhang, M.D., Ph.D, is a Professor of Epidemiology at UCLA School of Public Health, U.S.A. His major research areas are:
• Molecular epidemiology of smoking-related cancers
• Confirmation studies of SNPs identified in genome-wide association studies in smoking-related cancers
• Gene-environmental interaction between genetic markers and environmental factors• S. Lilly Zheng, M.D, is a Professor of Medicine and Director of the Genotyping Laboratory at Wake Forest University School of Medicine. U.S.A. Her major research areas are:
• High-throughput genotyping and sequencing
• Genetic epidemiology of prostate cancer• Gangqiao Zhou, Ph.D, is a Professor of Medical Genetics and Genomics in National Academy of Military Medical Science. His major research area is:
• molecular and genetics of complex diseases• Dingliang Zhu, M.D, is a professor of cardiology at Shanghai Institute of Hypertension, Shanghai, China. His major research area is:
• Molecular and genetics of cardiovascular diseases• Weimin Ye, Ph.D, is a Professor of Medical Epidemiology at Karolinska Institutet, Sweden. His major research areas are: Etiology of upper gastrointestinal diseases
• Topic of presentation: Molecular epidemiology of stomach cancer
 

喉咙不适，总觉得有东西在那里！异物感，不舒服极了！还以为是咽喉炎吗？说不定没这么简单。近日，69 岁患者傅阿姨，因咽部异物感一月余自行服药、处理后无明显好转，遂到石门县人民医院五官科门诊就诊，医师检查后凭经验感觉有点不妙，经 CT 显示「口咽左侧壁及左侧咽旁间隙肿块病变」，即以「口咽左侧病变性质待查」收住入院