搜索到 1000 条关于 61z토토디비삽니다~텔레그램DaisoDB⊆^ 的文章
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2018.01.10 看似「短暂性脑缺血发作」，诊断却出乎意料！
, 2003. 61(1): p. 117-20.5.van Gijn, J. and G.J. Rinkel, Subarachnoid haemorrhage... of three cases. AJNR Am J Neuroradiol, 2004. 25(10): p. 1676-9.23.Wu, Z., et al.
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2014.07.23 远视治疗进展
，此时为止，准分子激光效果较好。此外，固态激光平台（Pulzar Z1）也被用于矫正远视，对11眼小样本观察发现，UDVA改善为0.91（20/22），36...眼的不规则、不稳定，因此其较为特殊。对于此类病人而言以PRK为主的激光矫正仍为可选措施，并可避免深的放射切口所致角膜瓣相关并发症。对61名巴西患者进行随访
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2012.09.19 美式脊椎矫正手法培训班
。【食宿】：统一安排，费用自理。住宿标准40元-150元不等，餐费20元-30元/人/天。【交通路线】：深圳火车站西广场乘坐61路，人民公园站下
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2018.05.15 2016 年 9 月 距骨颈和距骨体骨折术后疗效观察
(SMD = 0.73,Z = 4.99,P<0.000 01) 及健侧下肢 (SMD = 0.69,Z = 4.71,P<0.000 01... (SMD = 0.42,Z = 2.41,P<0.05), 差异有统计学意义。结论急性单侧踝关节扭伤患者双下肢平衡功能均受损, 这些异常可能在受伤前就
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2018.05.15 2016 年 9 月 急性单侧踝关节扭伤患者双下肢平衡功能变化的 Meta 分析
(SMD = 0.73,Z = 4.99,P<0.000 01) 及健侧下肢 (SMD = 0.69,Z = 4.71,P<0.000 01... (SMD = 0.42,Z = 2.41,P<0.05), 差异有统计学意义。结论急性单侧踝关节扭伤患者双下肢平衡功能均受损, 这些异常可能在受伤前就
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2015.09.26 ERS2015：CARD9 蛋白亚型 1 或有助识别良恶性胸腔积液
）建立诊断模型并加以验证，并发现了有前景的蛋白标志物。研究结果表明，GA 诊断模型使用质荷比 3930.0 m / z 和 2942.8 m / z 建立，对 25...，该模型适用于良恶性胸腔积液的鉴别，其中最有前景的蛋白标志物为 CARD9 蛋白亚型 1，质荷比为 3930.9 m / z，而在恶性胸腔积液中低于该水平。更多
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2014.11.20 AHA2014：氯沙坦治疗马凡综合征疗效不优于阿替洛尔
动脉根部直径z评分最大变化/体表面积。次要终点主动脉根部直径绝对值变化率，主动脉返流变化率，主动脉分离、主动脉根部手术或死亡时间和不良事件发生等。研究结果表明阿替洛尔组和氯沙坦组患者平均年龄分别为11.5岁和11.0岁，基线主动脉根部z评分>3.0。阿替洛尔组和氯沙坦组基线校准主动脉根部z评分变化率无显著差异
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2014.08.06 ARIC 研究：中年高血压或与认知减退有关
Gottesman 及其同事发现，与基线期血压正常的人群相比，基线期有高血压、年龄在 48-67 岁之间人群的整体认知减退更明显，其 Z 评分得分降低 0.056（95...。在 20 年的随访时间内，与未治疗的高血压人群相比，接受降压药治疗患者的整体 Z 评分下降明显更少（0.050 VS 0.079）。研究者认为，「将中年高血压作为认知
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2012.09.19 首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
北京·2012年5月16-18日
上海·2012年5月21-23日尊敬的老师，您好！生理药代动力学模型（PBPK）在药物研发与监管中得到广泛应用意味着新时代的来临！它改变了动物试验和人体实验传统研究模式流程，指导制药企业项目决策及效率提高；FDA和EMA的使用及推荐，促使国外制药企业及学术单位相关研究者都在学习及掌握PBPK的应用。为促进我国在该领域的发展，力争与全球同步，凡默谷特邀美国Simulations Plus顶尖专家来华授课，让您了解及掌握PBPK知识、获悉国外最新应用、亲授多年使用经验，授课过程将以理论与实践相结合的形式进行。GastroPlus是由美国Simulations Plus公司研发的基于机制性生理模型的药代动力学、药效动力学(PBPK/PD)模拟软件，目前在FDA和几乎所有的全球顶尖制药公司中得到广泛应用，被誉为同类软件中的“黄金标准”。为确保培训效果，限额50人/班，第一轮通知发出后，已得到广大中国用户的积极响应和踊跃报名。报名从速！为何本次GastroPlus Workshop值得您参加？1）药物研发及监管中争相应用PBPK模型的时代已经来临！2）PBPK辅助药物研究可方便指导项目决策、节约成本、缩短时间；3）FDA已广泛采用PBPK模拟来制定法规和对新药及仿制药进行审批；4）FDA及各大制药企业对全球最权威的PBPK模拟软件GastroPlus倍加青睐；5）零距离接触Simulations Plus首席科学家，并参与学习的最新应用案例；6）您可免费获得一个月的GastroPlus软件试用。本次GastroPlus Workshop将让您受益良多：1）制药企业或CRO：有利于您理解您的客户或其他Sites实验方案设计思路、下一阶段决策及实验开展、合理设计实验方案；2）学术研究：启示您开辟新的药代、药剂等研究方向，剖析药物作用机制等；3）临床药理研究：合理设计临床试验方案，不同人群PK/PD研究等；4）法规部门：协助制定新药及仿制药政策和标准。报名方法：请您填写报名回执，并通过Email的方式反馈给我们。Email: training@pharmogo.com报名截止：2012年4月20日(北京培训班)/2012年4月30日(上海培训班)联系人：周伟,电话：021-61638583-8001报名确认：1）报名确认以凡默谷收到款项或报名者提供汇款凭证为准，凡默谷可先提供发票以供报销；2）会务组在接到报名后，将email或电话通知学员培训班相关事项。温馨提醒：学员必须自带已安装好Gastroplus程序的电脑参加培训，现场不提供电脑。
GastroPlus Workshop Course Instructors List
培训班详情：请下载附件参加北京培训班请点击下载：GastroPlus北京培训班第二轮通知/BeiJing GastroPlus-Intro-Workshop 2nd Notice参加北京培训班请点击下载：GastroPlus上海培训班第二轮通知/ShangHai GastroPlus-Intro-Workshop 2nd Notice
Michael B. Bolger
Chief Scientist
Simulations Plus Inc.
Dr. Bolger is Chief Scientist at Simulations Plus, he oversees a team of scientist / programmers at Simulations Plus, Inc. (Lancaster, CA) in the development of software programs (ADMET Predictor/Modeler, MedChem Studio/Designer, GastroPlus, DDDPlus, and MembranePlus) for estimation of biopharmaceutical properties, simulations of absorption and bioavailability, automated generation QSP/AR model building, in vitro dissolution, and cell culture permeability simulation.
As a faculty member at USC School of Pharmacy, his research was supported by several NIH basic science research grants and he published over 50 peer-reviewed publications. From 1989-1991 he served as a FDA National Science Advisor. He has served as a reviewer for numerous scientific publications. He is currently Adjunct Associate Professor of Pharmaceutical Sciences at USC.
Haiying Zhou, Ph.D.
Senior Scientist II
Simulations Plus Inc.
Dr. Zhou is Senior Scientist II at Simulations Plus, she focused on the development of modeling and simulation software for quantitative understanding of the pharmacokinetics and pharmacodynamics of drug candidates (GastroPlus), in vitro dissolution of active pharmaceutical ingredients and formulation excipients under various experimental conditions (DDDPlus). She received her M.S. degree in automation from East China University of Science and Technology (ECUST) in 2002 and her Ph.D in Biomedical Engineering from Case Western Reserve University (CWRU) in 2009. Her research interests in CWRU include multi-scale mathematical modeling of gas transport and cellular metabolism with emphasis on the metabolic regulation during different conditions, e.g. hypoxia and exercise.
John DiBella
Vice President of Marketing Simulations Plus Inc.
John DiBella is the Director – Marketing & Sales at Simulations Plus, He joined Simulations Plus in 2003 and has spent time working on the development of GastroPlus? and DDDPlus? software and consulting projects. Now, he leads the marketing & sales activities for the company while continuing to travel the world hosting training seminars.John obtained B.S. and M.S. degrees (with honors) in Biomedical Engineering from Case Western Reserve University in 2003. His graduate research was focused on computational modeling of physiological systems.
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2012.09.19 首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
首届中国PBPK模拟软件GastroPlus Workshop第二轮通知
北京·2012年5月16-18日
上海·2012年5月21-23日尊敬的老师，您好！生理药代动力学模型（PBPK）在药物研发与监管中得到广泛应用意味着新时代的来临！它改变了动物试验和人体实验传统研究模式流程，指导制药企业项目决策及效率提高；FDA和EMA的使用及推荐，促使国外制药企业及学术单位相关研究者都在学习及掌握PBPK的应用。为促进我国在该领域的发展，力争与全球同步，凡默谷特邀美国Simulations Plus顶尖专家来华授课，让您了解及掌握PBPK知识、获悉国外最新应用、亲授多年使用经验，授课过程将以理论与实践相结合的形式进行。GastroPlus是由美国Simulations Plus公司研发的基于机制性生理模型的药代动力学、药效动力学(PBPK/PD)模拟软件，目前在FDA和几乎所有的全球顶尖制药公司中得到广泛应用，被誉为同类软件中的“黄金标准”。为确保培训效果，限额50人/班，第一轮通知发出后，已得到广大中国用户的积极响应和踊跃报名。报名从速！为何本次GastroPlus Workshop值得您参加？1）药物研发及监管中争相应用PBPK模型的时代已经来临！2）PBPK辅助药物研究可方便指导项目决策、节约成本、缩短时间；3）FDA已广泛采用PBPK模拟来制定法规和对新药及仿制药进行审批；4）FDA及各大制药企业对全球最权威的PBPK模拟软件GastroPlus倍加青睐；5）零距离接触Simulations Plus首席科学家，并参与学习的最新应用案例；6）您可免费获得一个月的GastroPlus软件试用。本次GastroPlus Workshop将让您受益良多：1）制药企业或CRO：有利于您理解您的客户或其他Sites实验方案设计思路、下一阶段决策及实验开展、合理设计实验方案；2）学术研究：启示您开辟新的药代、药剂等研究方向，剖析药物作用机制等；3）临床药理研究：合理设计临床试验方案，不同人群PK/PD研究等；4）法规部门：协助制定新药及仿制药政策和标准。报名方法：请您填写报名回执，并通过Email的方式反馈给我们。Email: training@pharmogo.com报名截止：2012年4月20日(北京培训班)/2012年4月30日(上海培训班)联系人：周伟,电话：021-61638583-8001报名确认：1）报名确认以凡默谷收到款项或报名者提供汇款凭证为准，凡默谷可先提供发票以供报销；2）会务组在接到报名后，将email或电话通知学员培训班相关事项。温馨提醒：学员必须自带已安装好Gastroplus程序的电脑参加培训，现场不提供电脑。
GastroPlus Workshop Course Instructors List
培训班详情：请下载附件参加北京培训班请点击下载：GastroPlus北京培训班第二轮通知/BeiJing GastroPlus-Intro-Workshop 2nd Notice参加北京培训班请点击下载：GastroPlus上海培训班第二轮通知/ShangHai GastroPlus-Intro-Workshop 2nd NoticeMichael B. Bolger
Chief Scientist
Simulations Plus Inc.
Dr. Bolger is Chief Scientist at Simulations Plus, he oversees a team of scientist / programmers at Simulations Plus, Inc. (Lancaster, CA) in the development of software programs (ADMET Predictor/Modeler, MedChem Studio/Designer, GastroPlus, DDDPlus, and MembranePlus) for estimation of biopharmaceutical properties, simulations of absorption and bioavailability, automated generation QSP/AR model building, in vitro dissolution, and cell culture permeability simulation.
As a faculty member at USC School of Pharmacy, his research was supported by several NIH basic science research grants and he published over 50 peer-reviewed publications. From 1989-1991 he served as a FDA National Science Advisor. He has served as a reviewer for numerous scientific publications. He is currently Adjunct Associate Professor of Pharmaceutical Sciences at USC.
Haiying Zhou, Ph.D.
Senior Scientist II
Simulations Plus Inc.
Dr. Zhou is Senior Scientist II at Simulations Plus, she focused on the development of modeling and simulation software for quantitative understanding of the pharmacokinetics and pharmacodynamics of drug candidates (GastroPlus), in vitro dissolution of active pharmaceutical ingredients and formulation excipients under various experimental conditions (DDDPlus). She received her M.S. degree in automation from East China University of Science and Technology (ECUST) in 2002 and her Ph.D in Biomedical Engineering from Case Western Reserve University (CWRU) in 2009. Her research interests in CWRU include multi-scale mathematical modeling of gas transport and cellular metabolism with emphasis on the metabolic regulation during different conditions, e.g. hypoxia and exercise.
John DiBella
Vice President of Marketing Simulations Plus Inc.
John DiBella is the Director – Marketing & Sales at Simulations Plus, He joined Simulations Plus in 2003 and has spent time working on the development of GastroPlus? and DDDPlus? software and consulting projects. Now, he leads the marketing & sales activities for the company while continuing to travel the world hosting training seminars.John obtained B.S. and M.S. degrees (with honors) in Biomedical Engineering from Case Western Reserve University in 2003. His graduate research was focused on computational modeling of physiological systems.
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2017.01.21 2015 年内镜下结肠直肠息肉切除术相关指南与共识解读
cancer deaths[J]. CA Cancer J Clin, 2011, 61(4): 212-236.[19] Yoshii S, Nojima M...: guidance[Z]. London: National Institute for Healthand Clinical Excellence (UK
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2015.08.05 心血管内外科医师请关注：忽视基础查体所付出的惨痛代价
史，无家族遗传病史。入院查体：T 37.0℃ R 20bpm P 86bpm BP 200/100 mmHg 169 cm/61 kg...患者误诊的原因没有仔细考虑患者高血压的原因及仔细查体。来自 z00757600 的论坛回帖从这个病人整个诊疗过程来看，现在诊断为：先天性主动脉狭窄应该是没问题
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2020.07.24 生命科学质谱在精准医疗中的应用 | 第二期
（Stage I/II）预测的 sensitivity 有了非常显著的提高（94% V.S. 61%），而早期癌症的诊断将对病人的预后带来更为实质性的获益，因此这也... 1518-26.5.Zhang,Z., et al.,Three biomarkers identifiedfrom serum proteomic
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2018.07.31 国际第一部老年 3b 期或以上慢性肾脏病患者诊治指南解读
]Pei X, Bao L, Xu Z,et al. Diagnostic value of cystatin C...): 1773-1779.DOI:10.1093/ndt/gft063.[10]Liu J, Huang Z, Gilbertson DT,
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2017.11.30 脑深部刺激的机制
, Yianni, J., Loher, T. J. & Aziz, T. Z. Deep brain stimulation..., Z. Subthalamic span of beta oscillations predicts deep brain stimulation