, please click: http://www.genomeconference.org/pages/Abstract.aspxTop Poster

trials and regulatory affairs
A special showcase of top 10 Chinese innovative device companies and top 5 selected US/EU device companies interested in China

患者，男，16岁，进行性构音障碍、步态及行为异常。

基于双眼K-F环，低血铜，低铜蓝蛋白和24小时尿铜增加，初步诊断为肝豆状核变性（Wilson病），且最终通过分子分析确认（[Glu1382*]纯合子）。颅脑MRI显示弥漫性双侧皮质及皮质下异常。驱铜治疗后（D青霉胺）尽管患者发展为癫痫样抽搐（可能为皮质受侵入），但局部功能改善。伴广泛皮质及皮质下病灶的肝豆状核变性很罕见，但是当出现弥漫性白质脑病伴囊性变时还是需要考虑肝豆状核变性。查看更多

新疆药学会定于2009年7月15日在自治区科技馆召开国际植物药研究与开发论坛暨2009年新疆药学年会，同时举行新疆药学科技奖颁奖仪式。现将现将相关事宜通知如下：征文范围及要求：会议内容本次国际论坛会议邀请了以下专家：法国专家： 姓 名 工作单位① C. CIRARD教授 Universite de Franche-Comte授课内容：生药学② C. DEMOUGEOT教授 Universite de Franche-Comte授课内容：药理学③ D. VUITTON教授 Universite de Franche-Comte授课内容：药物研究方法学④ F. MUYARD教授 Universite de Franche-Comte授课内容：法国药学分子系统泰国专家： 姓 名 工作单位① K. CHOOTIP教授 Naresuan University授课内容：药剂学② D. PEKTHONG教授 Naresuan University授课内容：泰国药学分子系统

自从“第一届全球华人消化内镜学术大会”成功举办之后，四年过去了，消化内镜技术又有了飞速的发展，如NOTES、NBI、EUS、ESD等。为了进一步推进和提高我国消化内镜技术的发展，也为了展示全球华人消化内镜专家在该领域的成就，促进全球华人在该领域的学术交流，由中华医学会消化内镜学分会主办、第二军医大学承办的“第二届全球华人消化内镜学术大会”定于2009年9月10~13日在上海国际会议中心举办。届时世界著名的华人消化内镜专家，如曹世植（William Chao）、蓝庆民（Nib Soehendra）、钟尚志（Syndey Chong）、梁永昌（Joseph Leung）、沈祖尧（Joseph J.Y. Sung）、陈仰光(Yang K.Chen) 等就消化内镜的最新进展作精彩的专题学术报告，并作消化内镜最新技术的现场演示。同时，此次会议还增设了腹腔镜专场和现场手术演示。大会组委会热情欢迎各位同道参加此次盛会，共同促进我国消化内镜事业的不断发展和加强华人间和国际的学术交流。参加本次会

会议简介

According to Business Insights, an estimated $25bn worth of biologics will lose patent protection by 2016, creating a significant market opportunity for biosimilars. However, the reality is that biosimilar development is a risk-fraught activity that demands significant resources in R&D, manufacturing expertise, regulatory know-how, clinical-trial capabilities, and a high level of financial investment.

Biosimilar development is riddled with complexities, ranging from regulatory, to manufacturing to marketing, and is one of the most expensive propositions in the pharmaceutical industry. It is estimated that it costs between US$100-200 million to bring a biosimilar product to market. With so much at stake, biosimilars represent not only substantial growth but equally risk..

IBC’s 2nd Annual Biosimilars Asia 2011 Summit is the ONLY conference in Asia catering to this region’s specific queries. With unprecedented insights from leading innovators and biosimilar companies, you will network and learn how to strategically position your company to maximize your ROI. Biosimilars Asia 2011 is attended by key stakeholders in the region and beyond, enabling you to make informed strategic decisions.

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PAYMENT TERMS

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• Payment by telegraphic transfer in CNY must be made to:
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CANCELLATIONS SUBSTITUTION
Should you be unable to attend, a substitute delegate is welcome at no extra charge. Cancellations must be received in writing at least 10 business days before the start of the event, to receive a refund less 10% processing fee per registration. The company regrets that no refund will be made available for cancellation notifications received less than 10 business days before the event.IMPORTANT NOTE:
Please quote the name of the delegate, event title and invoice number on the advice when remitting payment. Bank charges are to be deducted from participating organisations own accounts. Please fax your payment details (copy of remittance advice, cheque or draft to +65 6508 2407.

Attendance will only be permitted upon receipt of full payment. Participants wishing to register at the door are responsible to ensure all details are as published. IBC Asia will not be responsible for any event re-scheduled or cancelled.


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。【报名回执】访问此链接填写报名回执（https://www.wjx.top/jq/80710449.aspx）【咨询请联系】QQ 号：2814500767邮箱

」、「雷米普利」、「氯沙坦」、「肼苯哒嗪」（非 ACE 类降压药）和「空白组」。C) 术后 14 天时的疤痕情况，「K」、「R」、「L」、「H」和「B」 依次为「ACE...疤痕大体情况。C) 术后 16 天小鼠疤痕的组织学切片（HE 染色）。K，KO to C57：ACE 基因敲除小鼠的骨髓移植到普通小鼠；10，ACE 10

上很难进行区分定性，今天我们就双侧丘脑病变的相关内容进行讨论，希望对大家临床工作有所帮助。1. 血管疾病1.1 基底动脉尖综合征（Top of basilar...，血清铜蓝蛋白降低，导致肝、脑、肾、角膜等部位异常铜沉积。典型临床症状表现为「三联征」：肝硬化、角膜「K-F 环」和基底节变性。主要累及壳核、桥脑、基底节、丘脑

）（即 S2TOP-BLEED 评分模型，见表1）。表 1 预测严重出血的S2TOP-BLEED 评分（来自多变量 Cox 回归模型）具体评分方法为，根据患者临床特征评估 S2TOP-BLEED 评分列表中每一栏分值，除了年龄相关的项目外，将其他所有项目分值想加得总分，再将总分代入图 1 所示风险分布图中，得到不同

明，使用远程医疗工具，如电话，互动视频和共享电子病历进行的多学科PTSD非现场干预，即创伤后应激障碍远程医疗服务（TOP）与常规护理（UC）相比，治疗效果显著提升...包括了2009年11月至2011年9月份在CBOCs接受治疗的265名主要生活在农村的退伍军人。所有患者均符合PTSD诊断标准，他们被随机分配接受TOP治疗（N

;vomiting of pregnancy and hyperemesis gravidarum (green top guideline 69).22 Jun 2016[4] 谢幸, 孔北华, 段涛. 妇产科学（第 9 版）[M]. 人民卫生出版社: 北京,2018:82.[5]Källén B,Use

].Transpl Infect Dis, 2016, 18(4):634- 636.[11] Shook B C, Lin K..Recent Advances in Developing Antiviral Therapies for Respiratory Syncytial Virus.[J].Top Curr Chem

K..Recent Advances in Developing Antiviral Therapies for Respiratory Syncytial Virus.[J].Top Curr Chem (Z), 2017, 375(2):40.[12] Glue P.The clinical pharmacology

of nausea and vomiting of pregnancy and hyperemesis gravidarum (green top guideline 69).22 Jun 2016[4] 谢幸, 孔北华, 段涛. 妇产科学（第 9 版）[M]. 人民卫生出版社: 北京,2018:82.[5]Käll

in America2014Delaware Today magazine, Top Doctors2013Best Doctors in America美国威尔明顿市阿...), FRCSEd, FCSHK, FHKAM(Surgery)香港皇家玛丽医院胸心外科主管和高级顾问。10.K.S. MurthyChief Pediatric

符合入选标准，444 例被确诊为隐源性肿瘤。以男性，年龄>70 岁，慢性肺疾病、贫血、血小板计数升高 （≧350000x1000/mm3），既往 VTE

了C1440512A批号的药品消费者应打1-800-444-4011联系Qualitest公司。消费者如果不能确定是否购买使用过该批次 的药品，应咨询药店或保健专业人员。药剂师

了C1440512A批号的药品消费者应打1-800-444-4011联系Qualitest公司。消费者如果不能确定是否购买使用过该批次 的药品，应咨询药店或保健专业人员。药剂师