(CAP1_6D)&montanide&GM_CSF_vaccine (CEA_vac) in pts with PC...;montanide&GM_CSF_vaccine (CEA_vac) in pts with PC

链接:http://play.google.com/store/apps/details?id=com.revsoft.doctormole

据美国物理学家组织网10月26日报道，美国麻省理工学院最近开发出一种新方法，能在实验皿上诱导神经元在精确的位置形成轴突连接。研究人员指出，通过这种方法，在可控制的条件下，能迅速、大规模地筛选新药，帮助提高老年痴呆患者的认知能力。相关论文发表在10月25日的《自然—通讯》杂志网站上。大脑约有1000亿个神经元，每个神经元通过突触和其它上千个神经元相连，它们释放神经传导素把信号 ...

Recommendations were developed using pragmatic systematic reviews of the literature

美国弗吉尼亚州国立临床研究所的James McKenney博士在ACC2012年会上报告了一个临床研究的结果，PCSK9的人单克隆抗体能够显著减低LDL-C及含ApoB脂蛋白。PCSK9是一种能破坏LDL受体的酶，功能获得突变导致高胆固醇血症，而功能丧失突变则伴随低水平LDL-C和冠心病发病率。尽管有他汀和其他调脂药物，很多患者仍无法达到LDL-C治疗目标。SAR236553/REGN727是一种高特异性抗PC ...

患者发生 CA 的情况进行详细描述。这项大规模研究经过严格筛选后招募了 852 名 cSLE 患者，其中 32 名（3.7%）发生 CA。受累部位主要集中在手

来自国立台湾大学医院 Yang 等在今年 6 月 1 日上午的 ASCO 壁报展示了培美曲塞+顺铂一线化疗后吉非替尼维持（PC/G）或吉非替尼单药（G）治疗... 例患者，1：1 分配至 PC/G 组和 G 组。PC/G 组治疗方案为培美曲塞 500 mg/m2+顺铂 75 mg/m2 21 天

Background. Hepatitis C virus (HCV) is spread through direct contact with blood, although alternative routes of transmission may contribute to the global burden. Perinatal infection occurs in up to 5% of HCV-infected mothers, and presence of HCV RNA in breast milk has been reported. We investigated the influence of breast milk on HCV infectiousness.Methods/Results. Human breast milk reduced HCV infectivity in a dose-dependent manner. This effect was species-specific because milk from various animals did not inhibit HCV infection. Treatment of HCV with human breast milk did not compromise integrity of viral RNA or capsids but destroyed the lipid envelope. Fractionation of breast milk revealed that the antiviral activity is present in the cream fraction containing the fat. Proteolytic digestion of milk proteins had no influence on its antiviral activity, whereas prolonged storage at 4°C increased antiviral activity. Notably, pretreatment with a lipase inhibitor ablated the antiviral activity and specific free fatty acids of breast milk were antiviral.Conclusions. The antiviral activity of breast milk is linked to endogenous lipase-dependent generation of free fatty acids, which destroy the viral lipid envelope. Therefore, nursing by HCV-positive mothers is unlikely to play a major role in vertical transmission.

已有研究表明，与溶剂型紫杉醇/卡铂相比，白蛋白结合型紫杉醇/卡铂（nab-PC）作为进展期NSCLC患者的一线治疗是有效的，且显著改善客观总体反应率...，随机分配到一线药物nab-PC治疗组及GC治疗组。nab-PC治疗组第1、8天，给予白蛋白结合型紫杉醇135mg/m2，以后每3周一次；卡铂,浓度

信息服务网站。其建立于 1996 年，并于 2005 年成功上市。除了针对一般人群健康的 WebMD.com，旗下还有面向专业医生的 Medscape.com，这两部分业务均在美国医疗互联网领域领先。仅在 2016 年，WebMD 的月独立访客就达到了 7,000 多万，并获得了超过 7 亿美元的收益。超过

Zhongshan Road II, Guangzhou 510080, China. easd04lyb@126.com.中山大学第一附属医院内分泌及糖尿病... previously found to be elevated in various types of human cancer and play a role