会议简介

According to Business Insights, an estimated $25bn worth of biologics will lose patent protection by 2016, creating a significant market opportunity for biosimilars. However, the reality is that biosimilar development is a risk-fraught activity that demands significant resources in R&D, manufacturing expertise, regulatory know-how, clinical-trial capabilities, and a high level of financial investment.

Biosimilar development is riddled with complexities, ranging from regulatory, to manufacturing to marketing, and is one of the most expensive propositions in the pharmaceutical industry. It is estimated that it costs between US$100-200 million to bring a biosimilar product to market. With so much at stake, biosimilars represent not only substantial growth but equally risk..

IBC’s 2nd Annual Biosimilars Asia 2011 Summit is the ONLY conference in Asia catering to this region’s specific queries. With unprecedented insights from leading innovators and biosimilar companies, you will network and learn how to strategically position your company to maximize your ROI. Biosimilars Asia 2011 is attended by key stakeholders in the region and beyond, enabling you to make informed strategic decisions.

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PAYMENT TERMS

Payment must be received 10 business days prior to the event. To take advantage of discounts with an expiry cut-off date, registration and payment must be received by the cut off date.

Payments by Singapore Dollars (S$)

Payments by RMB (CNY)

• Payment by telegraphic transfer in CNY must be made to:
  A/C Name:
  A/C No.: 720-031103-001
  Beneficiary Bank:
  Bank Address: No. 1000 Lujiazui Rind Road,
  Pudong, Shanghai 200120, P.R. China
  Bank Swift Code: HSBCCNSH

CANCELLATIONS SUBSTITUTION
Should you be unable to attend, a substitute delegate is welcome at no extra charge. Cancellations must be received in writing at least 10 business days before the start of the event, to receive a refund less 10% processing fee per registration. The company regrets that no refund will be made available for cancellation notifications received less than 10 business days before the event.IMPORTANT NOTE:
Please quote the name of the delegate, event title and invoice number on the advice when remitting payment. Bank charges are to be deducted from participating organisations own accounts. Please fax your payment details (copy of remittance advice, cheque or draft to +65 6508 2407.

Attendance will only be permitted upon receipt of full payment. Participants wishing to register at the door are responsible to ensure all details are as published. IBC Asia will not be responsible for any event re-scheduled or cancelled.


DATA PROTECTION
The personal information entered during your registration/order, or provided by you, will be held on a database and may be shared with companies in the Informa Group in the UK and internationally. Sometimes your details may be obtained from or shared with external companies for marketing purposes. If you do not wish your details to be used for this purpose, please contact Winnie Seah (Database) on winnie.seah@ibcasia.com.sg Tel: +65 6508 2468 or Fax: +65 6508 2408.

重要作用。目前已知TNFRSF1A有启动子区的-609G/T，-580A/G和-383A/C及第一外显子的+36A/G等SNP。在伴有血液疾病的侵袭性肺曲霉病患者中，TNFRSF1A +36A/G、-609A/G与侵袭性肺曲霉病易感性相关，且TNFR1-609G/T与TNFRl mRNA转录水平密切相关，携带TT基因型

HCC 患者（T1 或 T2 期）是否应接受切除或局部治疗（LRT）？推荐意见手术切除优于射频消融（RFA）。（证据质量：中；推荐强度：有条件）技术评论（1...肿瘤可能无法接受手术切除。（4）对 RFA 和手术切除进行比较的随机试验主要在东亚患者中进行。尚不清楚东西方人群统计学差异对不同治疗转归的影响。肝硬化是 HCC 的

血性心脏病和心房颤动病史，此次就诊原因为新发食管性吞咽困难。一周前，为治疗房颤，他接受了冠状动脉搭桥手术，左心房射频消融术（RFA）。一开始，胃肠病专家对他进行了评估

，如：射频联合 PEI（酒精注射）或者　TACE＋射频消融（RFA）。

;（TACE）和动脉放疗栓塞（TARE），而热射频消融包括射频消融（RFA）和微波消融（MWA），这两种方法均通过诱导肿瘤

清扫。SPN可以转移至腹膜、肝及淋巴结，再次手术可以提高生存率，对于无手术指征的肝转移病人，RFA及肝移植值得尝试。本研究只纳入了SPN手术病人，虽然SPN病人常规推荐

（RFA)、经导管动脉栓塞术/经导管动脉化疗栓塞（TAE/TACE)、HIFU 治疗等等，为学员与全球的医生和专家学者们提供一个活跃的平台，以交流临床经验及最新

://grants.nih.gov/grants/guide/rfa-files/RFA-AI-16-006.html。三、限项规定本项目属于国际（地区）合作研究项目，须遵循以下限项规定

这一期《月度好文精选》来晚啦，因为药药忙着处理「专业版拼团」活动的用户反馈。虽然晚了一些，但我保证，这一期好文章绝对超值！8 月用药经验 TOP 5《临床医生...给药？》《五张表教你同类药物如何等效剂量换算》8 月用药问答 TOP 5《用药问答：输液时突然休克，谁是罪魁祸首？》《用药问答：急诊遇糖尿病急性并发症

2017 年 6 月 13 日，备受瞩目的 2016 SCI 期刊影响因子正式发布，儿科领域的各期刊的 IF 值有何变化？一起来看下吧。儿科领域 Top 10...。儿科领域Top 30至于第 19 名，儿科君搜了去年的前 50 也没找到，只能说是一匹黑马。。。具体查询方法进入网站：web of science

界面：依次选中 Data1：C：C，Reorder，Up 三个选项至 Data1：C：C 上升至第一列，再点击 OK（或者直接点击 Top，置于顶端也可以得到... 下移，Top 置于顶端，Bottom 置于底端，Reverse 反转数据列顺序（即顺序有 ABCDE 改变为 EDCBA）。此外，进入 Format Graph

推荐书」的 TOP.5 榜单吧！这是根据「医生阅读行为」调研活动中的 2102 份有效问卷得出的榜单，有很多医生推荐同行看这些书。看了医生推荐的 Top

、生物技术类药物、神经系统药物、抗感染药物和复方药物为排名居 TOP 5 的治疗领域。其中，癌症仍是药品研发的核心领域，抗癌/抗肿瘤药物数量呈现显著增长态势，数量...，与 2015 年数据进行对比，可反映不同治疗类别在研药物数量的变化情况。从治疗类别 TOP 25 排名中发现，一般抗癌药 (在研药物 2071 个)、免疫类

, please click: http://www.genomeconference.org/pages/Abstract.aspxTop Poster

。【报名回执】访问此链接填写报名回执（https://www.wjx.top/jq/80710449.aspx）【咨询请联系】QQ 号：2814500767邮箱

trials and regulatory affairs
A special showcase of top 10 Chinese innovative device companies and top 5 selected US/EU device companies interested in China

本期「TOP list ·月度案例评选」是基于 6 月在丁香园医院汇平台上发布的文章，根据阅读量及点赞量呈现医疗行业「最受欢迎的品牌案例」TOP 10。医院汇努力为医疗行业从业者打造优秀品牌案例库，供行业宣传人士参考学习，也是众医院打造品牌曝光的重要营地。新闻资讯 TOP 10排名医院