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TOP2A 正常乳腺癌患者的 DBCG 07-READ 研究：多中心开放标签 III 期研究中，2012 名早期 TOP2A 正常的乳腺癌患者随机接受 6 周期...，无远处转移生存，死亡率都没有显著差异。3 级肿瘤从 DC 获益更多，1～2 级肿瘤从 EC-D 获益更多。证实早期 TOP2A 正常乳腺癌患者从辅助蒽环类药物

Intensive course:‘Model-based drug development: Incorporating population variability into mechanistic prediction of PK and modelling PK-PD' This event runs from 4th – 8th March 2013 at the Crowne Plaza Century Park, Shanghai, China.Delegates will learn how to simulate:• Metabolic drug clearance (CL)
• Metabolic drug-drug interactions (DDIs)
• Gut first-pass metabolism
• Oral drug absorption incorporating food effects and the impact of dosage form
• Effect of transporters and enterohepatic recirculation on kinetics and DDIs
• Drug distribution to different organs
• Population variability in drug concentration-time profiles
• Variation in kinetics in specific populations (paediatrics, ethnic groups, various disease populations)
• Data for therapeutic proteins
• Pharmacodynamic effects of different compounds
• Time-course of drug in plasma that fits observed clinical data (achieved by combining fitting techniques with IVIVE, PBPK and drug specific in vitro data)Click here to download the workshop flyer.Registration:

Online booking for Simcyp events is now handled through the Simcyp Members’ Area. Your saved profile is automatically captured on the booking form so there is no need to re-enter your contact details. Click here to link to the booking forms – you will be prompted for your Simcyp Members’ Area user name (email address) and password. If you have forgotten your log-in credentials please follow the instructions on-screen.If you have not yet registered for the Members’ Area please sign up now.For further information on any of Simcyp's events please contact Kelly Turton.Language AssistanceOur expert course tutors include many fluent Chinese speakers who will be able to assist with small group discussions and translate questions and answers after the lecture sessions. **Please note that the lectures and all course material will be in English**For Details Please Visitwww.simcyp.com/ProductServices/Workshops/20130304_Shanghai.htm?p=1

;go.Top 新型未来CT、静脉麻醉药瑞马唑仑和口服靶向抗肿瘤药吡咯替尼正式亮相。发布会上，西门子医疗系统有限公司、江苏恒瑞医药股份有限公司作为代表企业，分别发布各自的全新产品。SOMATOMgo.Top 新型未来CT 采用集成化的诊断平台，不仅

流水线，它整合了全球领先的全自动凝血分析仪 ACL TOP 700 LAS、市场上最完善的凝血检测菜单 HemosIL、专为凝血实验室设计的智能数据管理系统... 月底，新一代全自动凝血分析仪 ACL TOP Family 50 系列产品即将来到中国，这是全球第一个具有项目特异性分析前样本质量核查功能的凝血分析仪，被誉为

——制药企业质量负责人（国内大型）Quality head from top domestic company4、16:10-17:00无菌工艺关键... top 500 company17:00-17:20 演讲专家集体交流答疑 Experts Answering Questions17

》杂志、约见医药界以及PITOP100医药行业创新力评选等多渠道媒体品牌的大力推动下，「PharmMach国际制...！制药装备行业发展论坛医药包装创新论坛制药环保与洁净论坛最新制药机械、包装设备产品购销推介会「PITOP100」十大制药装备

《医药界》杂志、约见医药界以及PI TOP 100创新力评选等多渠道媒体品牌的大力推动下，「Contract Pharm 合同定制服务展」为企业打造了一个专业的...专场贸易配对会新产品、新技术推介会「PI TOP 100 」十大最具投资价值CRO企业颁奖盛典更多活动策划中，最新信息请关注

靶向药物。2013年全球最畅销抗肿瘤药物TOP20中的靶向药物市场销售规模合计326.78亿美元，占到抗肿瘤药物TOP20的64.45%。所谓海外代购抗癌药

，大家也同样清楚，潜在的就是存在很大不确定性的。世道就是这么颠覆的！当有人把“引用TOP100”看作“TOP100”时